Phase 2 Leukaemia Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 80 years, of any sex
• People who have been diagnosed with SBLPN (a specific type of lymphoma) confirmed by laboratory tissue or cell testing, and who need active treatment
• People who have not previously received any systemic (whole-body) treatment for SBLPN
• People with a general health and activity level rated 0 to 2 on a standard medical scale, meaning able to carry out at least some daily activities (confirm with trial site)
• People with a life expectancy of at least 6 months
• People whose blood count and organ function test results meet specific minimum levels, including adequate white blood cell counts, platelets, liver function, and kidney function (confirm with trial site for exact values)
• People who agree to use medically approved contraception throughout the study and for 4 weeks after treatment ends, if there is any possibility of becoming pregnant
• People who are willing to join the study voluntarily and sign a written consent form

Who may not be able to join:

• People diagnosed with a central nervous system disorder, including lymphoma affecting the brain or spinal cord, within the past year
• People who have had another type of cancer in the past 3 years, with some exceptions such as certain treated skin cancers or early-stage cervical conditions (confirm with trial site for full list of exceptions)
• People who have taken an experimental drug, antibiotic, or participated in another interventional clinical trial within the past 4 weeks
• People who have had major surgery (other than a lymph node biopsy) within the past 14 days, or who are expected to need major surgery during the study
• People who have previously used experimental treatments specifically targeting SBLPN
• People with active immune system conditions, autoimmune diseases, or who have been on higher-dose steroid medications within the past 7 days, or who are on any immune-suppressing treatment
• People with severe liver problems (such as serious jaundice, brain complications from liver failure, or related conditions), severe malnutrition, multiple organ failure, or severe kidney disease
• People with significant heart conditions, including serious heart failure, a heart attack within the past 6 months, uncontrolled irregular heartbeat, poorly controlled high blood pressure despite medication, or unstable chest pain
• People with bleeding disorders or blood clotting problems, or who have had a blood clot event within the past 3 months
• People with a known allergy or sensitivity to any ingredient in the study medications
• People who are pregnant, breastfeeding, or who are able to become pregnant but are unwilling or unable to use contraception
• People the trial doctor considers unsuitable for participation for other safety or practical reasons

Important: Always verify eligibility with the trial site directly before applying.