Obesity Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People diagnosed with Polycystic Ovary Syndrome (PCOS) based on specific criteria: irregular periods (cycles shorter than 21 days or longer than 35 days) and higher-than-normal male hormone levels, confirmed by blood tests.
• People who are classified as obese, meaning their weight is at or above the 95th percentile for their age group.
• Females between the ages of 12 and 18, who have had their period for at least 2 years.
• People whose PCOS symptoms and obesity have continued despite making lifestyle changes (such as diet and exercise) for at least 4 months.
• People who are in good overall health aside from the conditions listed above.

Who may not be able to join:

• People whose thyroid function blood tests came back abnormal at the screening visit.
• People with known or suspected diabetes, high fasting blood sugar, or abnormal results on a blood sugar marker test called HbA1c.
• People with a specific hormonal condition called non-classic congenital adrenal hyperplasia.
• People with a condition called hyperprolactinemia, which involves having too much of a hormone called prolactin in the blood.
• People with a personal or family history of a specific type of thyroid cancer (medullary thyroid carcinoma), a related genetic condition called MEN2, or a history of pancreas inflammation (pancreatitis).
• People who have been taking certain medications — including metformin, GLP-1 medications, the contraceptive pill, progesterone, or other insulin-sensitising medicines — for 6 weeks or more before the screening visit.
• People who are currently pregnant or who have been pregnant at any point.

Important: Always verify eligibility with the trial site directly before applying.