Lupus Trial, Recruiting NCT07175285 Sponsor: Bristol-Myers Squibb Condition: Lupus
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Lupus Trial, Recruiting

NCT07175285
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 16 or older at the time of signing the consent form.
  • People who have been formally diagnosed with systemic lupus erythematosus (SLE) — a chronic autoimmune disease — according to recognised international classification guidelines.
  • People whose SLE has not responded well enough to steroid treatments and at least 2 immunosuppressant therapies, one of which must be a biologic (a type of medication made from living cells), each used for at least 3 months. Poor response can include not responding, not responding enough, not sustaining a response, or being unable to tolerate the treatment (confirm with trial site).
  • People whose SLE is currently active, shown by specific disease activity scores and at least one positive blood test confirming the SLE diagnosis.
  • People with a specific form of SLE affecting the kidneys (called lupus nephritis) must have had a kidney biopsy within approximately 6 months before signing the consent form, showing a particular type and level of kidney involvement with less than 60% scarring in the kidney tissue (confirm with trial site).
  • People who have signed and dated an ethics-approved consent form before joining the trial.

Who may not be able to join:

  • People who are pregnant.
  • People who are already participating in another clinical trial involving an investigational (unapproved/experimental) treatment.
  • People who are unwilling or unable to attend the regular follow-up appointments needed to collect study information.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Bristol Myers Squibb, Bristol-Myers Squibb

Phone: 855-907-3286

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
8 October 2025
Est. completion
24 March 2028

Where this trial is recruiting

🇦🇷 Argentina 🇧🇷 Brazil 🇨🇦 Canada 🇫🇷 France 🇩🇪 Germany 🇮🇱 Israel 🇮🇹 Italy 🇯🇵 Japan Puerto Rico 🇪🇸 Spain 🇸🇪 Sweden 🇬🇧 United Kingdom 🇺🇸 United States

Primary endpoints

Number of of participants achieving Definition of Remission in Systemic Lupus Erythematosus (DORIS) at 6 months along with the 95% CI.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov