Phase 2 study

Recruiting Phase 2

Sources: ClinicalTrials.gov Checked: 14 October 2026 Not medical advice

This trial at a glance

Status Recruiting
Phase Phase 2
Sponsor Merck Sharp & Dohme LLC
Registry number NCT07209111
Started 4 December 2025 Today 16 October 2026 Estimated completion 9 April 2032

Where this trial is running

Trial sites and the status recorded for each
SiteCityState or countryStatus at this site
Prince of Wales Hospital-Medical Oncology ( Site 1003) Randwick NSW Recruiting
Westmead Hospital ( Site 1000) Westmead NSW Recruiting
Epworth Freemasons ( Site 1004) Melbourne VIC Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 14 October 2026 · not medical advice

Who can join

Age 18 Years and over
Sex Anyone, regardless of sex
Healthy volunteers Not accepted
Enrolment target 150

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

The main inclusion criteria include but are not limited to the following:

* Has locally advanced unresectable or metastatic solid tumor malignancy other than colorectal cancer and has progressed on, or following, standard of care systemic treatment

* Has a tumor that demonstrates the presence of Kirsten rat sarcoma (KRAS) G12C mutation

Exclusion Criteria:

The main exclusion criteria include but are not limited to the following:

* Has uncontrolled, significant cardiovascular disease or cerebrovascular disease

* Has known additional malignancy that is progressing or has required active treatment within the past 3 years

* Has known active central nervous system metastases and/or carcinomatous meningitis and/or primary brain tumors

* Has active infection, other than those permitted per protocol, requiring systemic therapy

* Has not adequately recovered from major surgery or has ongoing surgical complications

Dates on the record

Started 4 December 2025
Estimated completion 9 April 2032
Registry last updated 7 October 2026
Checked by Voxsanity 14 October 2026

Results, publications and the official record

Sources and dates

  • ClinicalTrials.gov – the record this page reformats
  • ClinicalTrials.gov processing date: 7 October 2026.
  • This page last checked by Voxsanity: 14 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.