Phase 1 Myasthenia Gravis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years old or older at the time of signing the consent form
- You have been diagnosed with Myasthenia Gravis (MG) at a moderate to moderately severe level, and your doctor does not expect you to need breathing support during the study
- Your MG symptoms significantly affect daily life, measured by specific scoring tools, with more than just eye-related symptoms (confirm with trial site for exact score thresholds)
- Your MG has not responded well enough to standard treatments such as steroids, immune-suppressing medications, or certain biological drugs, or there are no effective treatment options available for you
Who may not be able to join:
- You have previously received a type of advanced immune cell therapy called CAR-T, a T-cell engaging therapy, or a treatment targeting a protein called BCMA
- You have taken certain immune-suppressing medications not listed in the trial protocol within roughly the past 3 months (unless the medical team approves an exception)
- You have taken part in another clinical trial using a non-biological experimental treatment within about 4 weeks before joining this study
- You have taken part in another clinical trial using a biological experimental treatment within about 3 months before joining this study
- You received a live vaccine within 4 weeks before the screening visit
- You have a history of a serious brain condition called progressive multifocal leukoencephalopathy
- You have a history of a primary immune system deficiency or an inherited condition affecting part of your immune system called the complement system
- You have one or more serious ongoing health conditions, such as poorly controlled diabetes, advanced kidney disease, severe lung disease requiring oxygen, or respiratory failure
- You have any other serious medical condition or significant abnormal lab results that your doctor believes would make participation unsafe or affect the study results
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: +8618521520014
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Incidence and severity of treatment-emergent adverse events through end of study; Changes from baseline in vital signs through end of study: body temperature; Changes from baseline in vital signs through end of study: heart rate; Changes from baseline in vital signs through end of study: respiratory rate; Changes from baseline in vital signs through end of study: blood pressure; Changes from baseline in vital signs through end of study: pulse oximetry; Changes from baseline in ECG parameters through end of study: PR interval; Changes from baseline in ECG parameters through end of study: QRS in...
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.