Psoriatic Arthritis Trial, Recruiting NCT07220824 Sponsor: Janssen Research & Development, LLC Condition: Psoriatic Arthritis
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Psoriatic Arthritis Trial, Recruiting

NCT07220824
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with Psoriatic Arthritis (PsA) for at least 6 months, and your arthritis is currently active, meaning you have a minimum number of tender or swollen joints, or a blood test shows signs of inflammation
  • An ultrasound scan of your joints shows a certain level of joint swelling and inflammation in at least one or two of your joints at the start of the study (confirm with trial site)
  • You are starting a medication called Guselkumab for your Psoriatic Arthritis as part of your normal medical care, either at the time you join the study or within two weeks of your first visit
  • You have either never taken a biologic medication before, or you have only taken one biologic medication and/or one of the drugs apremilast or deucravacitinib in the past
  • You have at least one painful tendon or ligament attachment point (called enthesitis) that is both felt during a physical exam and visible on an imaging scan at the start of the study

Who may not be able to join:

  • You have previously taken Guselkumab, or you have used more than one biologic medication in the past for any condition
  • You have previously been treated with a type of medication called JAK inhibitors
  • You have a medical reason why you cannot safely take Guselkumab (confirm with trial site)
  • You are currently taking part in another clinical trial, or you finished one less than 30 days ago
  • You are already enrolled in another observational study involving Guselkumab that is run by the same organisation sponsoring this trial

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Janssen Research & Development, LLC Clinical Trial, Janssen Research & Development, LLC

Phone: 844-434-4210

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
4 December 2025
Est. completion
31 July 2027

Where this trial is recruiting

🇮🇹 Italy

Primary endpoints

Percentage Reduction From Baseline in Global OMERACT and EULAR Synovitis Score (GLOESS) at Week 12; Percentage of Participants Achieving Disease Activity Index for Psoriatic Arthritis (DAPSA) Low Disease Activity (LDA) Score Less Than or Equal to 14, at Week 24

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov