Brain Cancer Trial, Recruiting NCT07224451 Sponsor: Sheba Medical Center Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT07224451
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are 18 years of age or older
  • People who are able to read, understand, and sign a consent form agreeing to take part
  • People who are scheduled to have surgery to remove a tumor inside the spinal canal, where nerve monitoring is used during the operation

Who may not be able to join:

  • People who have a pacemaker or any other implanted electrical medical device
  • People who are pregnant or currently breastfeeding
  • People who have a serious medical, neurological, or psychiatric condition that may make it difficult to fully follow the study requirements
  • People who have a history of skull fractures or have previously had brain surgery
  • People whose overall health before surgery is rated as higher risk (above grade 2 on a standard anaesthesia health scale — confirm with trial site)
  • People who are currently taking blood-thinning medications
  • People who have a tear in the protective covering of the spinal cord that is causing spinal fluid to leak
  • People who have a history of seizures or epilepsy

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ran Harel, MD, Sheba Medical Center

Phone: +97235302993

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
16 October 2025
Est. completion
1 October 2027

Where this trial is recruiting

🇮🇱 Israel

Primary endpoints

Elevation in blood concentration of CNS biomarkers following BDF compared to biomarkers detected in CSF of the same subject. The overall incidence of BDF procedure-related AEs and SAEs, with severity graded according to CTCAE v5.0 criteria.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov