Phase 1 Long COVID Trial, Recruiting (NCT07224490)

Phase 1 Long COVID Trial, Recruiting NCT07224490 Sponsor: Stephanie B. Seminara, MD Condition: Long COVID

Printed from Voxsanity (voxsanity.com.au) — NCT07224490 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

Back to Long Covid

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

Women between 18 and 45 years old, or men between 18 and 60 years old
People with normal blood pressure (not too high)
People whose blood count (hemoglobin) is within a normal or near-normal range for their sex
People who are not currently taking medications that could affect reproductive hormones — or who are willing to stop taking such medications for a set period before joining (confirm with trial site)
Women must have a negative pregnancy blood test before joining
For "cases": People who have been diagnosed with post-COVID-19 syndrome (also known as long COVID)
For "controls": People who have had COVID-19 in the past but have NOT been diagnosed with post-COVID-19 syndrome

Who may not be able to join:

People with any medical, mental, or behavioral condition that a study doctor believes could interfere with completing the trial
People who drink more than 10 alcoholic drinks per week
People who are currently using illegal drugs
Women who are pregnant, trying to become pregnant, or currently breastfeeding
Women who have had both ovaries surgically removed, or have a history of breast cancer, blood clots, heart disease, stroke, clotting disorders, or unexplained abnormal vaginal bleeding

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 28 July 2026

Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.

Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 617-643-2308

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07224490

Sponsor: Stephanie B. Seminara, MD

Phase: Phase 1

Status: Recruiting

Condition: Long COVID

Trial contact: 617-643-2308

More information: https://clinicaltrials.gov/study/NCT07224490

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Women between 18 and 45 years old, or men between 18 and 60 years old
People with normal blood pressure (not too high)
People whose blood count (hemoglobin) is within a normal or near-normal range for their sex
People who are not currently taking medications that could affect reproductive hormones — or who are willing to stop taking such medications for a set period before joining (confirm with trial site)
Women must have a negative pregnancy blood test before joining
For "cases": People who have been diagnosed with post-COVID-19 syndrome (also known as long COVID)
For "controls": People who have had COVID-19 in the past but have NOT been diagnosed with post-COVID-19 syndrome

Who may not be able to join:

People with any medical, mental, or behavioral condition that a study doctor believes could interfere with completing the trial
People who drink more than 10 alcoholic drinks per week
People who are currently using illegal drugs
Women who are pregnant, trying to become pregnant, or currently breastfeeding
Women who have had both ovaries surgically removed, or have a history of breast cancer, blood clots, heart disease, stroke, clotting disorders, or unexplained abnormal vaginal bleeding

Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 28 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Phase 1

Sponsor

Stephanie B. Seminara, MD

Registry

ClinicalTrials.gov

Start date

10 March 2026

Est. completion

1 May 2030

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Difference in mean luteinizing hormone (LH) amplitude between cases and controls

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov