Phase 2 Lung Cancer Trial, Recruiting NCT07224971 Sponsor: Liza Villaruz, MD Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Recruiting

NCT07224971
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with advanced or spreading non-small cell lung cancer (a type of lung cancer) for whom a specific type of immunotherapy — called PD-1/PD-L1 therapy — is approved as a first treatment, either on its own or combined with other treatments (Group A).
  • People with advanced or spreading non-small cell lung cancer who have finished up to 4 rounds of initial treatment and whose cancer has stayed stable or responded well, and for whom PD-1/PD-L1 immunotherapy is approved as an ongoing maintenance treatment (Group B).
  • People with advanced or spreading solid tumour cancers (not limited to lung cancer) for whom PD-1/PD-L1 immunotherapy is approved as a first treatment, either alone or in combination (Group C).
  • People who have not previously received this type of immunotherapy (Groups A and C), or who received it as an initial treatment and are now moving to a maintenance phase (Group B).
  • People who are willing to be randomly assigned to take their treatment either early in the morning or later in the day or evening.
  • People for whom a treating doctor determines that PD-1/PD-L1 immunotherapy is appropriate under standard care guidelines and approved uses.
  • People who are able to understand and willing to sign a written consent form.
  • People who are able to read and write in English.

Who may not be able to join:

  • People who cannot receive PD-1/PD-L1 immunotherapy because of a previous allergic reaction to that treatment or any of its ingredients.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Liza Villaruz, MD, UPMC Hillman Cancer Center

Phone: 412-623-8963

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Liza Villaruz, MD
Registry
ClinicalTrials.gov
Start date
2 December 2025
Est. completion
1 May 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Real-world progression-free survival (rwPFS) - Cohort A

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov