Phase 3 Obesity Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• Your sleep study (overnight breathing test) must show that you stop breathing or have disrupted breathing at least 15 times per hour.
• Your Body Mass Index (BMI) — a measure of weight relative to height — must be 27 or higher at the time of your initial check-up.
• You must have tried to lose weight through diet and exercise at least once in the past without lasting success.
• You must not have used a breathing machine (such as a CPAP machine) for at least 4 weeks before joining, and you must be unwilling or unable to use one, and not plan to use one during the study.

Who may not be able to join:

• People who have previously had, or are planning to have, surgery on their upper airway for sleep apnea, or major surgery on their ears, nose, or throat.
• People who have significant structural differences in the face or skull that may affect their breathing.
• People whose sleep apnea is primarily caused by the brain not sending proper signals to breathe (central sleep apnea, 50% or more), or who have a specific breathing pattern during sleep called Cheyne Stokes Respiration.
• People currently using any device or treatment for sleep apnea (such as a CPAP machine or mouth device) unless they are willing to stop using it before and throughout the study.
• People with certain breathing conditions such as obesity-related breathing problems during the day, nerve or muscle diseases, or other health conditions that the study doctor believes could affect the trial results (confirm with trial site).

Important: Always verify eligibility with the trial site directly before applying.