Phase 2 Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 75 years at the time of signing the consent form
• People whose non-small cell lung cancer (a type of lung cancer) has been confirmed by laboratory testing of tissue or cells, and has spread locally or to other parts of the body
• People who have at least one tumour that can be measured using standard imaging guidelines (known as RECIST v1.1)
• People whose general health and ability to carry out daily activities is rated as fully active or restricted only in physically strenuous activity (a score of 0 or 1 on a standard scale doctors use)
• People who the treating doctor expects to survive for at least 12 weeks
• People whose liver, kidneys, and other organs are functioning well enough (confirm with trial site)
• People who have recovered from any side effects caused by previous cancer treatments
• People who agree to use highly effective birth control methods throughout the study treatment period
• People who voluntarily agree to and sign the informed consent form

Who may not be able to join:

• People who have cancer that has spread to the brain or spinal cord and is currently active or has not been treated
• People who have had another type of cancer in the three years before starting the trial
• People who have a history of serious heart, blood vessel, or blood clot conditions
• People who have HIV, active hepatitis B, or active hepatitis C
• People who have uncontrolled fluid build-up around the lungs, heart, or abdomen that keeps needing to be drained
• People who have a known allergy or sensitivity to the study drug (SKB571) or any of its ingredients
• People who have serious lung damage from previous lung-related complications
• People who have had lung inflammation not caused by infection that needed steroid treatment, or who currently have this condition
• People who have had major surgery within 28 days before starting the trial
• People who have received a live vaccine within 30 days before starting the trial, or who are expected to receive one during the study
• People who have taken certain medications that strongly affect how the body processes drugs (called strong CYP3A4 inhibitors or inducers, or BCRP inhibitors) within 2 weeks before starting the trial, or within 5 half-lives of that medication — whichever is longer (confirm with trial site)
• People who have received chemotherapy, immunotherapy, or biological cancer therapy within 4 weeks before starting the trial
• People who have an active infection requiring antibiotic or antiviral treatment within 14 days before starting the trial
• People who have been taking high-dose steroid tablets or other immune-suppressing medications for any condition within 14 days before starting the trial (confirm with trial site for specific dose thresholds)
• People with any other condition that the treating doctor believes could interfere with the study results or affect the person's safety

Important: Always verify eligibility with the trial site directly before applying.