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Phase 2 Endometrial Cancer Trial, Recruiting
NCT07232654
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Women aged 18 to 75 years old at the time of signing the consent form
- People who are well enough to carry out daily activities with little to no limitation (as measured by a standard medical scale called ECOG, with a score of 0 or 1)
- People whose doctors expect them to live for at least 3 more months
- People who have been diagnosed through lab testing with HPV-related cervical cancer of a specific type — squamous, adenocarcinoma, or adenosquamous carcinoma
- People whose cancer is at a particular stage (FIGO 2018 stage III to IVA), may have spread to nearby lymph nodes (confirmed by CT, MRI, or PET-CT scan), and has not spread to distant parts of the body
- People who have at least one area of cancer that can be measured using standard imaging criteria
- People whose blood, kidney, liver, and heart are functioning well enough to meet specific medical thresholds set by the trial (confirm with trial site for exact values)
- Women who could become pregnant must have a negative pregnancy test within 3 days before starting the trial drug, and must agree to use an approved form of contraception from the screening period until 120 days after the last dose
- People who are willing to follow all study procedures throughout the trial
Who may not be able to join:
- People whose cervical cancer is of a different cell type, such as neuroendocrine carcinoma or sarcoma
- People whose cancer has spread to distant parts of the body
- People who have previously had a full hysterectomy (complete removal of the uterus); those who have had other types of cervical surgery may still be considered (confirm with trial site)
- People who are unable or unwilling to receive a type of internal radiation treatment called brachytherapy
- People who have previously been treated with immune checkpoint inhibitors or other cancer immunotherapy medicines
- People who have taken high-dose steroid medicines (more than 10 mg per day of prednisone or an equivalent) or immune-suppressing medicines in the 2 weeks before joining — some exceptions apply for inhaled, skin-applied, or low-dose versions (confirm with trial site)
- People who have taken certain immune-boosting medicines (such as thymosin, interferons, or IL-2) within the 2 weeks before joining
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.
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Trial details
Status
Recruiting
Phase
Phase 2
Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Registry
ClinicalTrials.gov
Start date
11 November 2025
Est. completion
30 November 2027
Where this trial is recruiting
🇨🇳 China
Primary endpoints
2-year PFS rate
Can't join this trial?
Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.
Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.