Non-Alcoholic Fatty Liver Disease Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are Asian and between 18 and 65 years old.
• Your body weight falls within a specific range based on your height, with a BMI between 24.0 and 37.4 (using Chinese health standards).
• You have already tried to lose weight through diet or lifestyle changes for at least 2 months without enough success.
• You are willing to attend follow-up appointments as required by the trial.
• You are willing to sign a consent form agreeing to take part.

Who may not be able to join:

• You have had previous surgery on your stomach or digestive system that caused ongoing health problems.
• You currently have or have had significant digestive conditions such as severe acid damage to the esophagus, Crohn's disease, stomach ulcers, or any growths or tumors in the digestive tract.
• You have any condition that puts you at higher risk of bleeding in the upper part of your digestive system.
• You have a hiatal hernia larger than 2 cm, severe acid reflux, or acid reflux that needs two or more medications to control.
• You have a narrowing, pouch, or other structural problem in your throat or esophagus that could make it difficult to pass a medical camera (confirm with trial site).
• You have achalasia or another serious condition affecting how your esophagus moves food.
• You have a serious blood-clotting disorder.
• You have diabetes that requires insulin injections.
• You have ongoing or long-term abdominal pain.
• You have a condition affecting how your stomach moves or empties food, such as gastroparesis.
• You have significant liver disease or cirrhosis.
• You have a severe or poorly controlled mental health condition.
• You have problems with alcohol or drug dependence.
• You are not willing to follow a diet and behavior change program supervised by a doctor, or you are unwilling to attend regular follow-up visits.
• You regularly take anti-inflammatory painkillers (such as ibuprofen), blood thinners, or other medications known to irritate the stomach.
• You are unwilling or unable to take a specific type of acid-reducing medication (called a proton pump inhibitor) as directed during the trial.
• You are known to be allergic or sensitive to any part or material of the device used in this trial.
• You are currently pregnant or breastfeeding.
• You have serious heart or lung disease, or another serious illness affecting your whole body.
• You have tested positive for a stomach infection called Helicobacter pylori (H. pylori).
• You take certain time-sensitive medications — such as anti-seizure or heart rhythm drugs — that could be affected by changes in how quickly your stomach empties (confirm with trial site).
• You are currently taking steroid medications, drugs that suppress your immune system, or strong opioid painkillers.
• You have used any weight-loss medication in the past 3 months, or are currently using one.
• You have previously had any device placed inside your stomach for weight loss.
• You have taken part in another clinical trial that may affect your weight within the past 6 months.
• You have heart failure with symptoms, a significant irregular heartbeat, or unstable heart disease.
• You have a clinically significant breathing or lung condition.
• You have an autoimmune condition affecting your connective tissues (such as lupus or rheumatoid arthritis).
• Your life expectancy is less than one year, or you have severe kidney, liver, lung, or other serious medical illness.
• Your obesity is caused by a known genetic condition or hormone-related condition, such as an underactive thyroid or Prader-Willi syndrome.
• You have an eating disorder such as bulimia, binge eating disorder, or compulsive eating.

Important: Always verify eligibility with the trial site directly before applying.