Cystic Fibrosis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

Healthy volunteer group:

• You are 30 years of age or older

Bronchiectasis patient group:

• You are 18 years of age or older
• You have been diagnosed by a doctor with bronchiectasis, supported by symptoms (such as long-term cough and daily mucus production) and a chest CT scan confirming the condition
• You are able to do breathing/lung function tests following standard guidelines
• You are able to read, write, and are comfortable using electronic devices (such as a breath test device and a digital spirometer)
• You are willing and able to follow all study requirements
• Your condition is currently stable, or if you recently had a flare-up (worsening of symptoms), at least 4 weeks have passed since it ended before joining the main study visits
• You are able to give your signed agreement to take part in the study

Who may not be able to join:

Healthy volunteer group:

• You have been diagnosed with any breathing or lung condition, such as asthma, COPD, bronchiectasis, or pulmonary fibrosis
• You have an inflammatory condition such as rheumatoid arthritis, inflammatory bowel disease, or a similar connective tissue disease
• You currently have an active cancer (except for a common type of minor skin cancer called non-melanoma skin cancer)
• You have taken antibiotics for a chest or breathing infection in the past 4 weeks, or you currently have a sinus infection
• You currently smoke or have smoked in the past 3 months
• You are taking blood-thinning medication (anti-coagulants)
• You have any medical reason that would make the study procedures, including a bronchoscopy (a camera procedure to look inside the airways), unsafe for you

Bronchiectasis patient group:

• Your bronchiectasis is caused by scarring from another lung condition such as pulmonary fibrosis or cystic fibrosis
• Your main lung condition is something other than bronchiectasis, such as COPD or asthma (though having these as a secondary condition may still be acceptable — confirm with trial site)
• You have another serious health condition (for example, affecting your heart, liver, kidneys, nerves, mental health, or other body systems) that is not stable and could affect your safety, influence the study results, or prevent you from completing the study (confirm with trial site)
• You have had problems with alcohol or drug misuse in the past year that the doctor feels would make participation unsafe
• You currently have an active cancer (except for a common type of minor skin cancer called non-melanoma skin cancer)
• You are pregnant, breastfeeding, up to 6 weeks after giving birth, or within 6 weeks of stopping breastfeeding
• You have a cold, chest infection, or any other upper or lower respiratory infection or symptoms within 2 weeks of your first study visit
• Your mental state at the time of signing the consent form means you are unable to fully understand and agree to taking part
• You are considered by the medical team to be too unwell to participate, including having a terminal illness or organ failure
• You are involved in planning or running this study

Important: Always verify eligibility with the trial site directly before applying.