Endometrial Cancer Trial, Recruiting NCT07281430 Sponsor: National Cancer Institute (NCI) Condition: Endometrial Cancer
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Endometrial Cancer Trial, Recruiting

NCT07281430
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing and able to give documented informed consent to participate
  • People who are 25 years of age or older
  • People who have a cervix that has not been removed or surgically altered
  • People who have been referred for a colposcopy procedure because recent cervical cancer screening (within the past 12 months) showed a positive HPV test, an unclear cell result (ASC-US), or abnormal cell results — or who have been referred for a cervical excisional procedure
  • People who are willing and able to undergo a colposcopy, and if the treating doctor determines it is medically necessary, also a biopsy, endocervical curettage (sampling of the cervical canal), and/or a cervical excisional procedure

Who may not be able to join:

  • People who are currently pregnant or who gave birth within the past 3 months
  • People who have had a treatment to the cervix in the past 12 months — such as a LEEP procedure, cone biopsy, laser surgery, cryotherapy, or thermal ablation
  • People who have had a full or partial hysterectomy, including any surgery that removed the cervix, either by self-report or confirmed through medical records
  • People with known medical conditions that the trial investigator determines would prevent safe participation (confirm with trial site)
  • People who have previously taken part in the SHIP Trial or another cervical cancer screening study within the past 12 months, where participation included completing a self-collection
  • People who are currently experiencing unusual bleeding or pelvic pain

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 21 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
24 November 2025
Est. completion
30 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Clinical sensitivity for self-collected (SC) samples; Clinical sensitivity for clinician-collected (CC) samples; Clinical specificity for SC samples; Clinical specificity for CC samples; False positive rate (FPR) for SC samples; FPR for CC samples; False negative rate (FNR) for SC samples; FNR for CC samples; Sensitivity ratio for SC versus CC samples; Specificity ratio for SC versus CC samples; False positive (FP) ratio for SC versus CC samples; False negative (FN) ratio for SC versus CC samples; Positive percent agreement; Negative percent agreement

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov