Phase 1 Hypertension Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People who are pregnant and currently in hospital with a condition called preeclampsia (high blood pressure after 20 weeks of pregnancy, along with protein in the urine or signs that organs such as the kidneys or liver are not working normally)
- People who are expected to stay in hospital until they give birth
- People who are between 18 and 45 years old
- People who are between 26 weeks and 35 weeks and 6 days into their pregnancy at the start of the trial
- People whose condition is considered stable enough that delivery is not expected to be needed for at least 72 hours after receiving the study treatment
- People who are carrying one baby (not twins or more)
- People who have given written agreement to take part in the study
Who may not be able to join:
- People with certain placenta problems, such as the placenta covering the birth canal, the placenta separating early, the placenta growing into the uterine wall, or unexplained ongoing vaginal bleeding
- People whose baby is not growing as expected, or where the baby has a known major chromosomal or genetic condition
- People whose condition requires immediate delivery — for example, very high blood pressure that cannot be controlled, seizures, signs the baby is not coping, or fluid in the lungs
- People with an active infection that may affect the placenta
- People with certain serious health conditions, such as HELLP syndrome, advanced kidney disease, severe heart disease, an uncontrolled neurological condition, or lupus affecting the kidneys or brain
- People who have taken part in another clinical drug trial within the 30 days before joining this study
- People whose treating doctor considers there to be any other reason that taking part could pose a risk to the mother or baby
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Phone: 248-520-7361
Australian sites
0456 409 087
(03) 8345 3703
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
3 site(s) in Australia. Confirm current status and contact details directly with the trial site.
Primary endpoints
Incidence of treatment emergent events and adverse events of special interest when CBP-4888 is administered to pregnant participants; Determine recommended phase 2 dose
Can't join this trial?
Data last synced from ClinicalTrials.gov: 9 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.