Phase 1 Rheumatoid Arthritis Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- Adults who are in good general health (for the healthy participant group)
- Adults who have been diagnosed with idiopathic inflammatory myopathy (a condition where the immune system attacks the muscles), based on specific 2017 classification criteria used by rheumatology organisations
- Adults who have been diagnosed with systemic sclerosis (a condition affecting the skin and internal organs), based on specific 2013 classification criteria used by rheumatology organisations
- Adults who have been diagnosed with Sjögren's disease (a condition that commonly causes dry eyes and dry mouth), based on specific 2016 classification criteria used by rheumatology organisations
- All participants must use highly effective methods of contraception during the trial
Who may not be able to join:
- People who have had major surgery in the 12 weeks before the study starts, or who have planned major surgery during the study period
- People who have frequent infections or a current significant infection
- People who have active tuberculosis (TB), or a latent (inactive) TB infection that has not been treated
- People who currently have cancer, or who have had cancer or a disease affecting the lymph system within the past 5 years
- People who have a heart, lung, kidney, liver, hormonal, or digestive system condition that is not well controlled
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Mark Osterman, MD, MSCE, Xencor, Inc.
Australian sites
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
1 site(s) in Australia. Confirm current status and contact details directly with the trial site.
Primary endpoints
Percentage of participants with treatment emergent adverse events (TEAEs) and serious adverse events (SAEs)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.