Thyroid Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are willing and able to give your written agreement to take part in the study
- You are willing and able to attend all study appointments, including follow-up visits
- Your thyroid nodule can be reached using a specific treatment approach through the middle part of the thyroid gland (confirm with trial site)
- Your nodule has been confirmed as non-cancerous (benign) through one or more biopsy or needle tests, possibly combined with other imaging or molecular testing
- Your nodule is smaller than 80 ml in size
- Your vocal cords are working normally, as checked by an ultrasound scan
- You are experiencing symptoms such as a feeling of pressure in the neck, concerns about appearance, or worry about the nodule, and you are asking for it to be treated
- You have either a single thyroid nodule, or one nodule that is clearly the largest in a group of nodules, and it is well-defined on scan
Who may not be able to join:
- You have an implanted electronic medical device, such as a pacemaker or heart defibrillator
- Your nodule is mostly fluid-filled rather than solid (less than 70% solid)
- Your nodule contains calcium deposits
- You have a weakened immune system
- You have had radiation treatment to your neck in the past
- You have abnormal lymph nodes in your neck found during a check-up
- More than two of your close blood relatives (parents, siblings, children) have had thyroid cancer
- Your nodule has previously been treated with radiofrequency ablation or ethanol injection (alcohol treatment) — though prior treatment with a specific type called nsPFA is acceptable (confirm with trial site)
- You currently have a blood disorder or a condition that affects how your blood clots
- Your nodule appears to be very close to an important nerve in the neck (the recurrent laryngeal nerve), as seen on ultrasound
- You have a history of uncontrolled heart rhythm problems, uncontrolled high blood pressure, chronic liver disease, advanced kidney disease, a recent heart attack, or certain structural heart problems
- Your vocal cord on the opposite side of the nodule is not working normally
- You have known allergies to anaesthetic drugs
- You are pregnant at the time of screening or were pregnant within the 30 days before enrolling
- You have any other health condition or situation that the study doctor believes could put you at risk or affect the study results
- You have taken part in another medical trial or used an experimental device or drug within the 30 days before enrolling
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Ralph Tufano, MD, Sarasota Memorial Hospital
Phone: (314) 484-7033
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Volume Reduction Ratio (VRR)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.