PTSD Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have served in the U.S. military as a veteran
• People who speak English and are willing to sign consent and privacy forms
• Adults aged 70 years or younger
• People who scored 10 or higher on the GAD-7 anxiety questionnaire in the past week, which indicates at least a moderate level of anxiety
• People already taking antidepressants, provided they have been on that medication for at least 8 weeks and at the same dose for at least 4 weeks
• People who could potentially become pregnant must have a negative pregnancy test at the start of the trial and must agree to use an acceptable form of birth control throughout

Who may not be able to join:

• People with a lifetime diagnosis of bipolar type I disorder, schizophrenia, or other psychotic disorders, based on VA medical records
• People with a current problem with misuse of sedatives, sleeping pills, stimulants, inhalants, or opioids within the past 6 months, based on VA records and a clinical interview
• People diagnosed with moderate to severe alcohol or cannabis use disorder within the past 6 months, based on VA records and a clinical interview
• People with a history of severe traumatic brain injury, as defined by a specific medical assessment method (confirm with trial site)
• People with dementia or a related condition that progressively affects memory and thinking, as noted in their medical record
• People who have taken certain prohibited medications within the past 2 weeks (confirm the specific medication list with the trial site)
• People considered at high risk of suicide, including those who have had suicidal thoughts or behaviour within the past 90 days, or who screen positive on specific questions of a standard suicide risk questionnaire
• People who have had electroconvulsive therapy, vagus nerve stimulation, or transcranial magnetic stimulation within the past 6 months
• People who have an implanted device in their brain or nervous system, such as a deep brain stimulator
• People who have an implanted cardiac pacemaker
• People currently experiencing symptoms of trigeminal neuralgia (a nerve condition causing facial pain)
• People who have received a recognised, evidence-based form of therapy for anxiety, depression, or PTSD within the past 14 days — though people currently in non-evidence-based therapies such as supportive counselling may be eligible if they have been in that therapy for at least 4 weeks before the start of the study
• People who are pregnant during the treatment period
• People with a significant medical or surgical condition that would make the trial's electrical brain stimulation treatment unsafe — for example, an unstable heart condition, fear of electrical stimulation, skin irritation or wounds near the electrode sites, or metal fragments (such as shrapnel) near either electrode site
• People who are currently involved in legal proceedings to claim disability income for a mental health condition outside of the standard VA compensation and pension process

Important: Always verify eligibility with the trial site directly before applying.