Phase 2 Bipolar Disorder Trial, Recruiting NCT07288320 Sponsor: Neurocrine Biosciences Condition: Bipolar Disorder
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Phase 2 Bipolar Disorder Trial, Recruiting

NCT07288320
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with bipolar I disorder as your main condition.
  • You have had at least one manic episode in the past that needed medical treatment.
  • You are currently going through a manic episode (with or without mixed or psychotic symptoms) at the time of the trial.

Who may not be able to join:

  • You have an unstable or poorly managed ongoing health condition affecting the brain, liver, kidneys, heart, digestive system, lungs, immune system, or hormones that could interfere with the study.
  • You have been diagnosed with a cancer in the 90 days before the screening period begins.
  • Your main diagnosis is something other than bipolar I disorder.
  • You have previously been treated with a medication called clozapine for a type of psychosis that did not respond to other treatments.
  • You have been continuously hospitalised for mental health reasons for 30 days or more during the 90 days before screening begins.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Clinical Development Lead, Neurocrine Biosciences

Phone: 1-877-641-3461

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Neurocrine Biosciences
Registry
ClinicalTrials.gov
Start date
24 December 2025
Est. completion
1 February 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Change From Baseline in Young Mania Rating Scale (YMRS) Total Score at Day 21

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov