Phase 1 Endometrial Cancer Trial, Recruiting NCT07292818 Sponsor: UNC Lineberger Comprehensive Cancer Center Condition: Endometrial Cancer
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Phase 1 Endometrial Cancer Trial, Recruiting

NCT07292818
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are willing to provide written agreement to take part in the study and allow their personal health information to be used.
  • People who are willing and able to follow the study procedures, as determined by the study doctor.
  • People who are 18 years of age or older at the time of signing the consent form.
  • People who have a certain level of general physical functioning, as measured by standard medical scoring tools used in cancer care (confirm with trial site).
  • People who have been diagnosed with cervical cancer confirmed through tissue or cell testing, and whose treatment plan includes chemotherapy given alongside radiation therapy and brachytherapy (a type of internal radiation), except for those with known cancer spread into the rectum.

Who may not be able to join:

  • People who have an active infection that requires treatment with systemic medicines (medicines that work throughout the whole body).
  • People who are pregnant or currently breastfeeding, and breast milk cannot be stored for later use during the treatment period.
  • People who have a known allergy to products containing hyaluronic acid.
  • People who have a known inflammatory bowel condition, such as Crohn's disease or ulcerative colitis.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 22 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Shivani Sud, MD, UNC Lineberger Comprehensive Cancer Center

Phone: 919-966-4432

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
UNC Lineberger Comprehensive Cancer Center
Registry
ClinicalTrials.gov
Start date
2 February 2026
Est. completion
30 October 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Safety based on Grade 3 or higher adverse events associated with hyaluronic acid-based rectal spacer placement; Safety based on Patient Reported Outcome Report based on The Expanded Prostate Cancer Index Composite (EPIC) Bowel Assessment; Safety based on Patient Reported Outcome Report based on Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE); Distance between uterus/cervix/proximal vagina and rectum; Gel placement procedure time; Difficulty of gel placement

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov