Phase 1 Leukaemia Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 15 years or older, of any gender, race, or ethnicity.
- People who have a confirmed diagnosis of relapsed or refractory leukemia (leukemia that has come back or stopped responding to treatment), classified according to standard international guidelines.
- People whose liver is functioning well enough, based on specific blood test results being within acceptable ranges.
- People whose kidneys are functioning well enough, based on specific blood test results being within acceptable ranges.
- People whose heart is pumping normally, confirmed by an ultrasound of the heart showing a pumping strength above 50%.
- People who have at least one available donor aged 18 or older who is a partial tissue-type (HLA) mismatch, to provide a specific type of immune cells for the first stage of treatment. If that donor cannot also serve as a stem cell transplant donor, a separate stem cell transplant donor aged 18 or older must also be available (confirm with trial site for donor matching details).
- People (or their legal representatives) who are willing to sign a consent form confirming they understand and agree to take part.
- The donor must also meet the trial site's health requirements for donating blood stem cells and be willing to sign their own consent form.
Who may not be able to join:
- People with an active infection or uncontrolled bleeding that has not been brought under control.
- People with significant heart conditions, such as serious irregular heartbeat, heart failure, a heart attack within the past 6 months, or moderate to severe heart disease based on a standard heart function scale.
- People with an autoimmune disease that is not under control, or who require ongoing medication to suppress their immune system.
- People with a history of a severe reaction to a blood transfusion or infusion.
- Women who are breastfeeding, women who could become pregnant and have a positive pregnancy test, or women who could become pregnant and are not willing to use adequate contraception during the trial.
- People with a psychiatric condition or cognitive (thinking or memory) difficulty that, in the treating doctor's judgement, would make it difficult to follow the trial requirements.
- People who have had major surgery within the 4 weeks before enrolling in the trial.
- People who have another life-threatening illness in addition to leukemia, or another serious uncontrolled medical condition.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Bo Cai, MD, Department of Hematology, the Fifth Medical Center of Chinese PLA General Hospital
Phone: +861066947168
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Graft-Versus-Host Disease (GVHD); Infections; Hematological Toxicity
Can't join this trial?
Data last synced from ClinicalTrials.gov: 22 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.