Phase 2 Lung Cancer Trial, Recruiting NCT07323056 Sponsor: Shanghai Pulmonary Hospital, Shanghai, China Condition: Lung Cancer
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Phase 2 Lung Cancer Trial, Recruiting

NCT07323056
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You must be willing and able to sign a consent form to take part in the study
  • You must be 18 years old or older
  • You have been diagnosed with a type of lung cancer called non-small cell lung cancer (NSCLC) that has a specific gene change called an EGFR mutation, confirmed by a tissue test
  • Your lung cancer is at an advanced stage (stage IIIA, IIIB, or IIIC), confirmed by scans, and a medical team has decided that surgery right now is not the right option for you
  • You have not had any cancer treatments (such as chemotherapy or targeted therapy) before
  • Your doctors can identify at least one area of cancer that can be measured on scans, using a standard set of measurement rules
  • Your lungs are healthy enough that you could tolerate surgery if needed
  • You are generally active and able to care for yourself, with little or no limitation on daily activities (confirm with trial site if unsure about this score)

Who may not be able to join:

  • You have had an allergic reaction to the study drug Sacituzumab Tirumotecan or any of its ingredients
  • You have had an allergic reaction to the study drug Limertinib or any of its ingredients
  • You have had another type of cancer (other than this lung cancer) at any point, or you have previously received a transplanted organ from another person
  • You have had major surgery in the 4 weeks before starting the trial (routine diagnostic biopsies do not count)
  • You have a history of drug abuse, long-term heavy alcohol use, or you are living with HIV/AIDS
  • You have an autoimmune disease (where your immune system attacks your own body) that is currently active or could come back
  • You are currently taking steroid medications at a relatively high dose, or any other medicines that suppress your immune system, within 14 days before starting the trial (confirm with trial site for specific details)
  • You have previously been treated with a type of targeted therapy called an EGFR-TKI, or a type of drug called a TROP2 ADC

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 13 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 021-65115006

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Shanghai Pulmonary Hospital, Shanghai, China
Registry
ClinicalTrials.gov
Start date
1 January 2026
Est. completion
1 June 2026

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Pathological complete response (pCR) rate

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 13 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov