Phase 2 Alopecia Areata Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are an adult male.
• You are between 18 and 59 years old.
• You have been diagnosed with male-pattern baldness at a moderate to significant level (known as Hamilton-Norwood scale stages III to V — confirm with trial site if unsure of your stage).
• Your body weight is at least 50 kg (about 110 lbs) and your body mass index (a measure of weight relative to height) is 18.0 or above.
• You are a non-smoker.
• You are in generally good health with no significant medical conditions.
• You are willing and able to receive multiple injections and attend all required appointments throughout the study.
• You are comfortable having blood drawn.

Who may not be able to join:

• You have a significant medical history or current condition affecting your lungs, liver, kidneys, blood, digestive system, hormones, immune system, or nervous system, or you have had a major illness or surgery in the past 3 months.
• You have diabetes that is not well controlled.
• You have a condition that affects your immune system's ability to function properly.
• You have a history of significant heart disease.
• You have a history of certain heart rhythm risk factors (confirm with trial site).
• You have any skin conditions affecting your scalp.
• You have a history of or signs of raised, thick scarring on your skin (keloids or hypertrophic scars).
• Your hair loss is caused by something other than male-pattern baldness, such as alopecia areata, scarring, or other conditions.
• You have previously had a surgical hair restoration procedure or hair transplant.
• Your scalp has ever been treated with radiation.
• You use semi-permanent hair products.
• You plan to wear an occlusive wig, hair extensions, or hair weaves during the study.
• You have used over-the-counter hair regrowth products or cosmetic hair treatments within 2 weeks before your first dose.
• You have used topical or local treatments on the scalp (confirm specific products with trial site).
• You have used certain non-topical medications within 24 weeks before your first dose (confirm with trial site).
• You have used anti-cancer or chemotherapy drugs that could affect hair loss within the past 12 months.
• Your scalp hair loss in the treatment area is caused by an injury, disease, or medical treatment.
• You currently have an infection that requires antibiotic, antifungal, antiparasitic, or antiviral medication.
• You have had any cancer in the last 5 years (except for certain skin cancers that were fully removed by surgery).
• You have tested positive for HIV, hepatitis B, or hepatitis C.
• You test positive for recreational drugs, alcohol, or nicotine at your screening visit or before your first dose.
• You have received any vaccines within 14 days before your first dose.
• You have donated blood or plasma, lost more than 500 mL of blood, or received a blood transfusion within the timeframes specified by the trial (confirm exact timeframes with trial site).
• You have taken part in another clinical trial involving an experimental drug within the past 60 days (or longer, depending on the drug — confirm with trial site).
• You drink more than 10 standard alcoholic drinks per week, or more than 2 in a single day on a regular basis.
• You have had surgery or been hospitalised in the 3 months before screening, or have surgery planned during the study.
• You have a known allergy or sensitivity to the study drug or any of its ingredients.
• You are unwilling or unable to follow the study requirements, or you refuse to give your informed consent.
• Any other condition that the study doctor feels would make participation unsuitable for you.

Important: Always verify eligibility with the trial site directly before applying.