Study

Recruiting Not a phased study

Sources: ClinicalTrials.gov Checked: 11 October 2026 Not medical advice

This trial at a glance

Status Recruiting

Phase Not a phased study

Sponsor Cosmetique Active International

Registry number NCT07335003

Started 1 July 2025 Today 16 October 2026 Estimated completion 1 March 2029

Where this trial is running

Trial sites and the status recorded for each
Site	City	State or country	Status at this site
Sydney Melanoma Diagnostic Centre, Royal Prince Alfred Hospital	Camperdown	NSW	Recruiting

voxsanity.com.au · trial sites from public registries · registry record synced 11 October 2026 · not medical advice

Who can join

Age 60 Years and over

Sex Anyone, regardless of sex

Healthy volunteers Not accepted

Enrolment target 80

The official eligibility criteria

Registry text, reproduced exactly. These are the words the trial's sponsor published on ClinicalTrials.gov. They have not been edited, shortened or rewritten, and they are written for researchers rather than for patients.

Inclusion Criteria:

1. Adult outpatients ≥ 60y old with at least 11 clinically typical actinic keratosis lesions, including at least one on the face;

2. Patient having understood and signed a written informed Consent Form to participate in the study indicating the potential participant's willingness to undergo the study procedures and complete the study.

Exclusion Criteria:

1. Atypical actinic keratosis lesions including suspected squamous cell carcinoma and basal cell carcinoma (could be present at screening and treated but cannot be present at 1st visit);

2. History of \>2 squamous cell carcinomas;

3. Known history of immunodepression whatever its cause in the past year;

4. Participants who cannot undergo skin biopsies, with a history of scarring problems or who have developed adverse effects from the use of local anesthesia will also be excluded.

5. Participant using interferon or interferon inducers, immunomodulators, cytotoxic or immunosuppressive drugs, corticosteroids, retinoids, other keratolytics or have received investigational drug within 4 weeks before enrolment

6. Participant having active, localized or systemic infection other than the AK lesions

7. Participant having any dermatological affection within the treated and adjacent area according to the Investigator judgement

8. Participant having a present or past skin condition that according to Investigator judgment, deems inappropriate for study participation

9. Participant having other significant medical conditions that according to Investigator Judgment, deems inappropriate for study participation

10. Participant having a known hypersensitivity, allergy or contraindication to any ingredients contained within the cosmetic products,

11. Participant taking part or intending to take part in another study for 30 days prior to D1 visit, and 30 days following last study visit. that according to Investigator judgment, deems inappropriate or may interfere for study participation

12. Participant using light-based devices such as but not limited to PUVA (Psoralen Ultraviolet A therapy), IPL (Intense Pulsed Light), laser, LED (Light Emitting Diode) devices or tanning beds, within 4 weeks before enrolment.

13. Participant having applied any topical product on the investigational areas the day of enrolment visit,

14. Participant under legal guardianship or incapacitation.

15. Participant being psychologically incapable of signing informed Consent Form and unable to comply with the protocol requirements according to investigator judgment.

Dates on the record

Started 1 July 2025

Estimated completion 1 March 2029

Registry last updated 12 January 2026

Checked by Voxsanity 11 October 2026

Results, publications and the official record

No results are posted on the official record yet.
No publications are listed on the official record yet.
Official record and contacts on ClinicalTrials.gov – contact details for each site are kept there, and are not copied onto this page.

Sources and dates

ClinicalTrials.gov – the record this page reformats
ClinicalTrials.gov processing date: 12 January 2026.
This page last checked by Voxsanity: 11 October 2026.

Voxsanity reformats data from public registries into this layout. It does not edit, interpret or add to what the registry published.

Not medical advice.

Individual trial records are refreshed on a rolling basis rather than all at once, so a record may be up to several weeks old. Each trial page and trial card shows the date its own record was last synced. Where a record has lagged, its status, sites and enrolment can differ from the current registry state in either direction, so check the registry link on the trial page before acting on them.

Letter for your doctor

A one-page summary of this trial to print or email to your GP. It carries the registry's own record of the trial and its eligibility criteria, and nothing Voxsanity has written about whether it suits you.

Voxsanity

Clinical trials recruiting in Australia, from the public registries · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial, which may be relevant to my care:

Trial: NCT07335003

Sponsor: Cosmetique Active International

Phase: Not a phased study

Status: Recruiting

More information: https://clinicaltrials.gov/study/NCT07335003

Eligibility criteria, as the registry published them

Reproduced exactly, unedited. Written for researchers rather than for patients.

Inclusion Criteria:

Adult outpatients ≥ 60y old with at least 11 clinically typical actinic keratosis lesions, including at least one on the face;
Patient having understood and signed a written informed Consent Form to participate in the study indicating the potential participant's willingness to undergo the study procedures and complete the study.

Exclusion Criteria:

Atypical actinic keratosis lesions including suspected squamous cell carcinoma and basal cell carcinoma (could be present at screening and treated but cannot be present at 1st visit);
History of >2 squamous cell carcinomas;
Known history of immunodepression whatever its cause in the past year;
Participants who cannot undergo skin biopsies, with a history of scarring problems or who have developed adverse effects from the use of local anesthesia will also be excluded.
Participant using interferon or interferon inducers, immunomodulators, cytotoxic or immunosuppressive drugs, corticosteroids, retinoids, other keratolytics or have received investigational drug within 4 weeks before enrolment
Participant having active, localized or systemic infection other than the AK lesions
Participant having any dermatological affection within the treated and adjacent area according to the Investigator judgement
Participant having a present or past skin condition that according to Investigator judgment, deems inappropriate for study participation
Participant having other significant medical conditions that according to Investigator Judgment, deems inappropriate for study participation
Participant having a known hypersensitivity, allergy or contraindication to any ingredients contained within the cosmetic products,
Participant taking part or intending to take part in another study for 30 days prior to D1 visit, and 30 days following last study visit. that according to Investigator judgment, deems inappropriate or may interfere for study participation
Participant using light-based devices such as but not limited to PUVA (Psoralen Ultraviolet A therapy), IPL (Intense Pulsed Light), laser, LED (Light Emitting Diode) devices or tanning beds, within 4 weeks before enrolment.
Participant having applied any topical product on the investigational areas the day of enrolment visit,
Participant under legal guardianship or incapacitation.
Participant being psychologically incapable of signing informed Consent Form and unable to comply with the protocol requirements according to investigator judgment.

Not medical advice. Voxsanity reformats information published by public registries. It does not give medical advice and is not a substitute for talking to your doctor.