Brain Cancer Trial, Recruiting NCT07335315 Sponsor: Mayo Clinic Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT07335315
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

For the Contrast-Based part of the trial:

  • You have been diagnosed with Cushing's disease, or you need surgery to remove a certain type of brain tumor near the pituitary gland (a non-corticotroph adenoma)
  • You have agreed to have a specific type of surgery to remove the tumor through the nose (called transsphenoidal resection)

For the Non-Contrast-Based part of the trial:

  • You are having any type of pituitary gland surgery performed by one of the surgeons designated for this study
  • Your surgery is planned to include the use of a specific ultrasound device (BK ultrasound) during the operation, without contrast dye

Who may not be able to join:

For the Contrast-Based part of the trial:

  • You are not able to give your own consent, and your legal guardian or representative has also declined to give consent on your behalf
  • You have a known or suspected allergy to the contrast agent (microbubble) used in the procedure, or to any of its ingredients, such as a substance called polyethylene glycol (PEG)
  • You are a woman of childbearing age and your pregnancy test before the procedure comes back positive
  • You have a certain type of heart condition where blood can flow in the wrong direction between the chambers of your heart (confirm with trial site)
  • You have a known allergy to a substance called perflutren, which is used in the contrast agent

For the Non-Contrast-Based part of the trial:

  • You are not able to give your own consent, and your legal guardian or representative has also declined to give consent on your behalf

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 26 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Ian Mark, MD, Mayo Clinic

Phone: 507-293-7354

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
Registry
ClinicalTrials.gov
Start date
19 June 2024
Est. completion
1 January 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Scoring of non-contrast ultrasound images; Scoring of contrast-enhanced ultrasound images; Scoring of pituitary MRI images

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 26 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov