PTSD Trial, Recruiting NCT07336251 Sponsor: White River Junction Veterans Affairs Medical Center Condition: PTSD
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PTSD Trial, Recruiting

NCT07336251
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged between 19 and 70 years old
  • People who are eligible for VA (Veterans Affairs) healthcare
  • People with moderate to severe PTSD, confirmed by a specific assessment tool (called the CAPS) that scores at least 25, taken within 7 days of being enrolled in the trial
  • People who agree to have their CAPS assessment audio recorded
  • People for whom a specific brain stimulation measurement (called Motor Threshold) can be successfully taken using the TMS device during the screening process
  • Women who could become pregnant must be using an accepted form of birth control, such as contraceptives or abstinence
  • People who are able to read, understand, and sign the consent form for the trial

Who may not be able to join:

  • Women who are currently pregnant or breastfeeding
  • People for whom an MRI scan is not safe or is not recommended (confirm with trial site)
  • People currently taking the medication clozapine at any dose, or bupropion at more than 300mg per day
  • People who have a cardiac pacemaker or an implantable defibrillator
  • People who have any metal object in their head, such as a cochlear implant (dental work in the mouth does not apply)
  • People with a significant brain or nervous system condition, such as a history of stroke, a brain tumour, or epilepsy
  • People who have had a seizure within the past year
  • People currently experiencing psychosis or mania
  • People with significant suicidal thoughts
  • People with unstable medical conditions
  • People with a current alcohol or substance use disorder (not including nicotine) that would interfere with their ability to take part in the trial
  • People who have received specific PTSD therapies called CPT or PE within the past 2 months
  • People whose dose of certain antidepressants — Fluoxetine, Paroxetine, Sertraline, or Venlafaxine — has been changed in the past 2 months
  • People who are colour blind
  • People who are currently taking part in other research studies
  • People who have an aneurysm clip
  • People who have a metal foreign body in or around the eye (for example, metal shavings)
  • People who have any other implanted device, such as a pump or infusion device
  • People with shrapnel injuries or metal fragments in their body

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Bradley Watts, US Department of Veterans Affairs

Phone: 802-295-9363

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Sponsor
White River Junction Veterans Affairs Medical Center
Registry
ClinicalTrials.gov
Start date
15 January 2026
Est. completion
1 January 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Frequency and intensity of PTSD symptoms as assessed by the CAPS-5; 20 item self-report of PTSD symptoms assessed by PCL-5

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov