Lung Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with non-small cell lung cancer (a specific type of lung cancer) that has spread to other parts of the body (stage IV).
• People whose lung cancer tumour has a low level of a protein called PD-L1 (less than 50% of tumour cells showing this protein).
• People whose cancer does not have certain specific gene changes (such as EGFR mutations or ALK fusions) that would make them eligible for targeted treatments.
• People who have not previously received any systemic treatment (such as chemotherapy, targeted therapy, or immunotherapy) for their advanced lung cancer — or people who received earlier treatments (before or after surgery, or combined with radiation) where their cancer did not return until more than 6 months after finishing that treatment.
• People who are generally able to carry out basic daily activities, based on a standard medical rating scale (a score of 0–2 on the ECOG scale — confirm with trial site if unsure what this means).
• People aged 18 years or older.
• People who have at least one area of cancer that can be measured on a scan, according to standard medical criteria.
• People whose blood counts, kidney function, and liver function meet certain minimum levels as assessed by blood tests (confirm with trial site for specific thresholds).
• People who are willing to participate voluntarily, sign a consent form, and attend follow-up appointments.

Who may not be able to join:

• People who are unable to complete the initial health assessments required before the trial begins.
• People who are pregnant or currently breastfeeding, or people with psychiatric, intellectual, or language difficulties that may affect participation.
• People with autoimmune diseases or blood disorders that require long-term use of steroids or medicines that suppress the immune system.
• People who currently have another active cancer in a different part of the body.
• People who have taken part in another clinical trial of an experimental drug or device within the 30 days before the planned start of this trial.
• People who are HIV-positive, have other conditions affecting their immune system, or have previously had an organ or stem cell transplant.
• People whose overall health, mental state, or personal circumstances may prevent them from completing the trial, as judged by the trial doctor.
• People who have active skin infections, wounds, or sores at areas of the body where acupuncture needles would be placed.
• People who have an implanted heart pacemaker or any other active electronic medical device implanted in their body.
• People who have a severe fear of needles that would prevent them from receiving the needle-based treatment involved in this trial.
• People who have received acupuncture or any similar needle-based therapy within the 6 weeks before joining the trial.
• People who currently have active lung inflammation (pneumonitis), including inflammation caused by radiation treatment, that requires steroid treatment.
• People who currently have an active infection requiring antibiotic, antifungal, or antiviral treatment (though the trial site may reconsider once the infection is fully treated).
• People with active tuberculosis, or serious uncontrolled illness such as uncontrolled seizures, dementia, or unstable heart, lung, liver, or kidney disease.

Important: Always verify eligibility with the trial site directly before applying.