Phase 1 Bladder Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- People aged 18 or older who are able to give written consent to participate
- People with an advanced solid tumour (not originating in the brain or spinal cord) that has been confirmed through a tissue or cell sample
- People whose cancer has at least one area that can be measured using standard imaging criteria (known as RECIST v1.1)
- People who are fully active or have only minor restrictions in physical activity (as rated on a standard scale called ECOG PS, at level 0 or 1)
- People with a life expectancy of at least 12 weeks, as assessed by their doctor
- People with liver cancer (hepatocellular carcinoma) who have relatively well-preserved liver function, rated as Child-Pugh Class A
- People whose kidneys, liver, blood, and other organs are functioning adequately based on specific blood test results outlined in the study protocol
- People who are not currently pregnant or breastfeeding
Who may not be able to join:
- People who have not waited long enough after finishing previous cancer treatments, as specified in the study protocol
- People still experiencing side effects rated moderate or severe (Grade 2 or higher) from previous cancer treatments, with some exceptions
- People who have had a different cancer diagnosis within the past 2 years, with some exceptions
- People with HIV, hepatitis B, or acute hepatitis C that is not currently under control
- People who have cancer that has spread to the brain or spinal cord and is not stable or being treated
- People with an active autoimmune disease, or one that required medical treatment within the past 3 years
- People who have received any organ transplant, including a bone marrow or stem cell transplant from a donor
- People with a significant, active heart or blood vessel condition
- People with a known active problem with alcohol or drug misuse
- People with a psychiatric condition that would prevent them from understanding and signing the consent form
- People with liver cancer (hepatocellular carcinoma) who have needed a procedure to drain fluid from the abdomen, or who have had a brain condition related to liver failure requiring medical treatment, within the past 6 months
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Anthony El-Khoueiry, MD, University of Southern California
Phone: +1 843 203 1031
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Frequency, type and severity of dose limiting toxicities and adverse events
Can't join this trial?
Data last synced from ClinicalTrials.gov: 21 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.