Phase 1 OCD Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You are 18 years old or older
- You have been diagnosed with OCD (obsessive-compulsive disorder) based on a structured diagnostic interview
- Your OCD is at least moderate in severity, based on a standard OCD rating scale score
- You have tried at least one standard recommended treatment for OCD that did not work well enough
- You are considered safe to live independently
- You are willing and able to stop taking certain medications and supplements at least two weeks before the study treatment begins (some medications, such as fluoxetine/Prozac, must be stopped at least six weeks before)
Who may not be able to join:
- You currently have, or have a history of, a psychosis (a condition involving a break from reality) or an active substance use disorder
- A close family member (parent, sibling, or child) has a history of psychosis or bipolar disorder
- You have certain heart conditions, such as a history of stroke or heart attack, uncontrolled high blood pressure, a fast resting heart rate, an abnormal heart rhythm, or a specific type of irregular electrical signal in your heart
- You have certain metabolic or blood sugar conditions that are not well controlled, including specific diabetes complications
- You have serious kidney or liver problems
- You have unstable lung disease (COPD) or severe sleep apnea
- You have a mental health condition that puts you or others at serious risk, or a personal or close family history of bipolar disorder
- You regularly take sedatives, narcotic pain medications, or antipsychotic medications
- You are pregnant, breastfeeding, planning to become pregnant, or planning to donate sperm within three months after the last dose of study medication
- You or your partner could become pregnant and you are unwilling or unable to use highly effective birth control during the study and for three months after the last dose
- You have made a suicide attempt in the past 12 months
- You have any condition that makes it unsafe for you to have an MRI scan, such as a pacemaker, certain metal implants, or certain electrical medical devices in your body
- You have used recreational drugs (including marijuana, cocaine, opioids, sedatives, or hallucinogens) in the week before your screening appointment
- You weigh less than 45 kilograms (approximately 99 pounds)
- You have an allergy or significant intolerance to chocolate or cocoa
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Francisco Moreno, MD, University of Arizona
Phone: (520) 626-8000
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Yale Brown Obsessive Compulsive Scale; Adverse Event (AE) Tracking log; Visual Analogue Scale (VAS)
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.