Phase 1 Vitiligo Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You are between 18 and 60 years old and have been diagnosed with a type of vitiligo (called non-segmental vitiligo) on your face or neck
• You have 1 to 3 vitiligo patches on your face and/or neck, with a combined size between 6 cm² and 40 cm², where at least 75% of the skin in those areas has lost its colour
• Your vitiligo patches have been present for at least 3 months before the study starts
• Your vitiligo covers no more than 20% of your total body surface area
• Your facial vitiligo patches have been present for 5 years or less, with no new patches or worsening in the last 3 months
• You are generally in good health, with no other conditions that might affect your ability to take part
• You are not currently using any treatments for vitiligo, including prescription, over-the-counter, or cosmetic products
• You agree not to use any other vitiligo treatments (including light or laser therapies) for 4 weeks before and during the study
• You agree not to apply any creams, lotions, or other skin products to the treatment area during the study, unless told to by the study doctor
• You are able to understand and follow all study requirements
• If you are a woman who could become pregnant, you have a negative pregnancy test and agree to use a reliable form of contraception or abstain from sex throughout the study

Who may not be able to join:

• Women who are pregnant, breastfeeding, or who could become pregnant and are not using reliable contraception
• People who have a different type of vitiligo, such as segmental or mixed vitiligo
• People whose vitiligo only affects the genitals or the hands and feet
• People who have a history of skin cancer or pre-cancerous skin changes in the area to be treated
• People who have used any vitiligo treatments (topical or systemic) in the 4 weeks before the study starts
• People who are currently using steroid creams on the face or immune-suppressing therapies within the last 4 weeks
• People who have used biological, experimental, or investigational treatments in the 3 months before the study starts that could affect the results
• People who have a known allergy or sensitivity to any ingredient in the study treatment
• People who have previously had a surgical procedure for vitiligo, such as a skin cell transplant (MKTP) or similar surgery
• People with an uncontrolled thyroid condition or other medical conditions that could interfere with the study
• People who have used certain medications in the 4 weeks before the study, including oral or injected steroids, UV light therapy (UVA/UVB), non-prescription UV light devices, JAK inhibitor medications (oral or topical), or chemotherapy drugs
• People who have previously tried JAK inhibitor treatments and did not respond to them
• People with significant abnormalities in blood tests or vital signs, as assessed by the study doctor
• People who have active skin conditions, inflammation, or other skin issues on the face or neck that could affect the study
• People who are currently in another clinical trial, or who have been in one within the last 30 days
• People who are unable or unwilling to follow the study requirements
• People with mental health or medical conditions, or personal circumstances, that the study doctor feels would make participation unsuitable or unsafe
• People with significant alcohol or drug misuse issues, or a history of not following study instructions reliably

Important: Always verify eligibility with the trial site directly before applying.