Muscular Dystrophy Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

For people with myotonic dystrophy (DM):

• You are between 18 and 65 years old
• You have been diagnosed with myotonic dystrophy type 1 or type 2, either through genetic testing or by a doctor based on your symptoms (if diagnosed by symptoms only, a close blood relative must have had genetic confirmation and agree to share that information)
• You have noticeable symptoms such as muscle weakness or muscle stiffness/spasms (myotonia)
• You are able to walk on your own without using a walker
• You are able to understand and agree to take part in the study yourself

For healthy comparison participants (control subjects):

• You are between 18 and 65 years old
• You are in good general health with no significant medical or neurological conditions
• You are able to understand and agree to take part in the study yourself

Who may not be able to join:

• You have a cardiac pacemaker, a defibrillator, metal implants in your body, or anything else that would make it unsafe for you to have an MRI scan
• You have used certain muscle-affecting medications or supplements (anabolic or catabolic agents) within the past year
• You have a history of lower back or leg surgery, lower back nerve problems, or nerve damage in your limbs
• Your BMI (a measure of body weight relative to height) is above 35, as this can make positioning in the MRI scanner difficult
• You are pregnant
• For the muscle biopsy part of the study: you have a history of bleeding disorders or are taking blood-thinning medication (note: if you take anti-inflammatory painkillers like ibuprofen, you may be asked to stop taking them 7 days before the biopsy — confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.