Phase 1 Rheumatoid Arthritis Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People whose body mass index (a measure of body weight relative to height) falls between 18 and 32
• People who have been diagnosed with Systemic Lupus Erythematosus (SLE) — a chronic immune system disease — for at least 6 months, and whose diagnosis meets a specific set of recognised medical classification standards
• People with SLE who are already taking at least one background medication for their condition
• People who have been diagnosed with Rheumatoid Arthritis (RA) — a condition where the immune system attacks the joints — for at least 6 months, and whose diagnosis meets a specific set of recognised medical classification standards

Who may not be able to join:

• People who currently have an active infection, or who needed hospital care or antibiotic/antiviral treatment for an infection within the past 8 weeks (minor nail fungal infections are generally not counted — confirm with trial site)
• People with a history of serious, recurring, or long-term infections
• People known to be infected with Hepatitis B, Hepatitis C, or HIV
• People with signs of active, latent (dormant), or inadequately treated tuberculosis (TB)
• People with a significant or uncontrolled health condition in any part of the body that is unrelated to RA or SLE
• People with RA whose joint disease began before the age of 17
• People who have another ongoing inflammatory condition (separate from SLE or RA) that could affect how disease activity is measured in the trial
• People with a history of cancer, unless the cancer was a fully treated non-melanoma skin cancer or a localised cervical cancer removed completely by surgery, and only if they have been cancer-free for at least 5 years before the trial start date
• People who had major surgery within the 3 months before the screening stage, or who have major surgery planned during the trial period
• People who have had a heart attack, unstable chest pain, or significant heart failure symptoms within the past 6 months
• People with severe long-term lung disease that requires ongoing oxygen therapy
• People who currently have, or show signs of, a lymphoproliferative disease — a group of conditions involving abnormal growth of immune cells, including lymphoma

Important: Always verify eligibility with the trial site directly before applying.