Thyroid Cancer Trial, Recruiting
Who may be able to join
AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI
Who might be able to join this trial:
- You have been diagnosed with a specific type of thyroid cancer called papillary thyroid carcinoma, confirmed by a needle biopsy or tissue sample.
- Your thyroid tumor(s) are each no larger than 2.0 cm (about the size of a small grape) at their widest point.
- Your cancer has not spread outside the thyroid gland, and there is no sign it has reached nearby lymph nodes or other parts of the body.
- Your tumor is located a safe distance (more than 2 mm) away from important nearby structures like the windpipe, food pipe, or major blood vessels — or it can be safely treated using a technique that moves those structures out of the way.
- Your cancer is classified as an early stage (T1b or lower), with no known spread to lymph nodes or distant organs.
- You are either not healthy enough for surgery due to other medical conditions, or you have chosen not to have surgery.
- You are 18 years old or older.
- You are not pregnant at the time of treatment.
- You are able to understand the study information and agree to take part by signing a consent form.
Who may not be able to join:
- There is any sign — on scans or physical examination — that your cancer has spread to lymph nodes or other parts of the body such as the lungs or bones.
- Your tumor has grown beyond the edges of the thyroid gland into surrounding tissue.
- Your tumor has heavy calcium deposits throughout it.
- Your tumor is too close (within 2 mm) to important nearby structures and cannot be safely treated, even with techniques to move those structures.
- You have previously had surgery or any other ablation treatment (such as heat, laser, alcohol, or microwave therapy) on the same tumor being studied.
- You have been diagnosed with a more aggressive or fast-growing type of thyroid cancer (other than papillary thyroid carcinoma).
- You are pregnant or breastfeeding when enrolling in the study.
- You have a condition that affects blood clotting, or you take blood-thinning medications that cannot be safely stopped before the procedure.
- You have a serious illness that is expected to significantly shorten your life expectancy (less than 5 years).
- You are unable to attend follow-up appointments or follow the study schedule, or you are not able to make your own medical decisions.
- You have an implanted electrical device in your body, such as a pacemaker or nerve stimulator.
- You have an active infection in your neck — including a skin infection or thyroid inflammation — at the time of the planned treatment.
- You have significant scarring or changes to the structure of your neck from previous neck surgery or radiation therapy that would make the procedure unsafe.
Important: Always verify eligibility with the trial site directly before applying.
Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.
Contact this trial
Principal Investigator: Sangeet Ghai, MD, University Health Network - Toronto General Hospital
Phone: 416-500-5737
Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.
GP referral letter
Print a one-page summary to share with your doctor.
Trial details
Where this trial is recruiting
Primary endpoints
Local Cure Rate of Papillary Thyroid Cancer (PTC) following Radiofrequency; Safety of the RFA procedure
Can't join this trial?
Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.