Early Phase 1 Brain Cancer Trial, Recruiting NCT07387666 Sponsor: University of Texas Southwestern Medical Center Condition: Brain Cancer
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Early Phase 1 Brain Cancer Trial, Recruiting

NCT07387666
Recruiting Early Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with glioblastoma (a type of brain tumor).
  • You have been newly diagnosed and have not yet had any surgery, radiation, chemotherapy, or other treatment for this tumor.
  • You are 18 years of age or older.
  • You are able to carry out most daily activities and care for yourself — your doctor can assess this using a standard performance scale (confirm with trial site).
  • Your liver, kidneys, and blood counts are within acceptable ranges as measured by recent blood tests (confirm with trial site).
  • You agree to use reliable contraception (such as hormonal methods, barrier methods, or abstinence) before, during, and for 7 days after completing the treatment — this applies to all men and to women who could become pregnant.
  • If you could become pregnant, this means you have not had your uterus or both ovaries removed, or have not gone through menopause for at least 12 consecutive months.
  • You are able to understand the study information and are willing to sign a consent form agreeing to take part.

Who may not be able to join:

  • You have received chemotherapy, radiation, or any other cancer treatment within the past 4 weeks.
  • You have not yet fully recovered from side effects of a previous cancer treatment (with some exceptions — confirm with trial site).
  • You are currently taking part in another clinical trial that is also testing a treatment for this cancer.
  • Your brain tumor has spread from another part of the body (known as brain metastases).
  • You have had a serious allergic or hypersensitivity reaction to a drug similar to Acetadote (the treatment used in this trial).
  • You have an uncontrolled serious illness, such as an active infection, heart failure, unstable chest pain, irregular heartbeat, or a mental health condition that could make it difficult to follow the study requirements.
  • You are currently pregnant or breastfeeding, due to potential risks to the baby.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 28 July 2026
Early Phase 1 studies are small, early exploratory studies that come before the main Phase 1 to 3 testing, so a standard phase success rate does not apply.

Contact this trial

Phone: 214-648-7097

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Early Phase 1
Registry
ClinicalTrials.gov
Start date
18 June 2026
Est. completion
1 July 2027

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

To determine the effect of Acetadote on glioblastoma metabolism as measured by MRS.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 28 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov