Phase 2 Head and Neck Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People aged 18 to 79 years old.
• People who have been diagnosed with a head or neck cancer confirmed by laboratory testing — this includes cancers of the nasopharynx, mouth, throat, voice box, salivary glands, nasal cavity, sinuses, and similar areas.
• People whose cancer has stopped responding to at least two previous standard treatments, including treatments with cetuximab and an immunotherapy drug.
• People whose doctors estimate they are likely to live for at least 3 more months.
• People who are reasonably active and able to care for themselves, based on a standard medical activity scale scored 0 to 2 (confirm with trial site).
• People whose blood test results before treatment show a neutrophil count above 2000/mm³ and a platelet count above 100,000/mm³ (these are types of blood cells measured in routine tests).
• People whose liver and kidney function tests before treatment fall within acceptable ranges: bilirubin below 1.5 mg/dL, liver enzymes (AST or ALT) no more than 1.5 times the normal upper limit, and kidney markers (creatinine below 1.5 mg/dL and clearance above 60 mL/min).
• People who are willing to follow the trial schedule and visits, and who are able to give written consent to participate.

Who may not be able to join:

• People whose doctors estimate they are likely to live for less than 3 months.
• Women of childbearing age who have a positive pregnancy test.
• People with other serious ongoing health conditions that could affect their safety or ability to take part in the trial (confirm with trial site).
• People with active mental health conditions that would prevent them from understanding the study or signing a consent form.
• People with serious blood clotting problems or an active infection that currently requires treatment through an intravenous drip.
• People who have had a different type of cancer within the past 5 years — except for certain skin cancers or a very early-stage form of thyroid cancer that has already been treated with the aim of curing it.
• People with serious heart rhythm problems or high blood pressure that is not controlled by treatment (blood pressure above 150/90 mmHg).
• People who still have side effects from previous cancer treatments that have not improved to a mild or resolved level, with some exceptions such as hair loss or mild nerve-related symptoms (confirm with trial site).
• People who test positive for HIV, or who have active hepatitis B or hepatitis C infections, based on specific blood test results (confirm with trial site).
• People who the trial doctors consider unsuitable for any other reason that could affect their safety or ability to follow the trial plan.

Important: Always verify eligibility with the trial site directly before applying.