Phase 3 Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who are willing to take part voluntarily and sign a consent form
• People who have been confirmed through a tissue or cell sample to have cervical cancer (specifically squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma) that is not suitable for major surgery and/or intensive radiation treatment or combined chemotherapy and radiation
• People who are able to provide a tissue sample from their primary or a secondary (spread) tumour
• People who have at least one tumour that can be measured using standard imaging methods
• People with a good general level of functioning — able to carry out daily activities with little or no restriction (confirm with trial site regarding the specific scoring scale used)
• People whose major organs such as liver, kidneys, and bone marrow are working adequately
• People whose life expectancy is estimated to be at least 12 weeks

Who may not be able to join:

• People who have untreated or active cancer that has spread to the brain or spinal cord lining
• People who have significant fluid build-up around the lungs, heart, or abdomen that is causing symptoms or is difficult to control
• People who have had, or currently have, another type of cancer
• People who have had a hole or abnormal opening in the gut or urinary/reproductive tract, or are considered at risk of developing one, within the 3 months before joining
• People with a known or suspected lung condition involving scarring of lung tissue
• People who have had a bowel blockage, or signs of one, within the 3 months before joining
• People with poorly controlled heart conditions or significant heart disease
• People who have had a blood clot in an artery or vein within the 3 months before joining
• People who have had a serious infection within the month before joining
• People with active hepatitis B or active hepatitis C, as determined by specific blood test results at screening
• People who have had active tuberculosis within the past year, or who had active tuberculosis more than a year ago that was not properly treated
• People with a history of immune system deficiency, a positive HIV test, other immune conditions present from birth or acquired, or a history of organ transplant
• People who have received any systemic cancer treatment within 28 days before joining
• People with uncontrolled psychiatric conditions, or a known history of alcohol misuse, drug abuse, or substance dependence, or who are currently incarcerated
• People with any other condition that the trial doctor believes could increase risk, affect results, or make participation unsuitable (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.