Rare Disease Trial, Recruiting (NCT07422454)

Rare Disease Trial, Recruiting NCT07422454 Sponsor: Imagine Institute Condition: Rare Disease

Printed from Voxsanity (voxsanity.com.au) — NCT07422454 — Data sourced from ClinicalTrials.gov. Verify directly with the trial site before attending. Not medical advice.

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Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

As a patient with one of these conditions:

You have been diagnosed with one of the following conditions: a skull growth condition linked to FGFR signaling (a gene pathway), achondroplasia or hypochondroplasia (types of dwarfism), osteogenesis imperfecta (brittle bone disease), or Pierre Robin sequence (a condition affecting jaw and airway development)
You have previously agreed to allow your biological samples (such as blood or tissue) to be stored in one of three specific medical collections related to bone and developmental conditions (confirm with trial site)
You have had a brain or facial scan (CT or MRI) done as part of your regular medical care

As a "control" participant (someone without these conditions):

You have visited the Genetics, Pediatrics, or Maxillofacial Surgery departments at Necker hospital and do NOT have any of the conditions listed above
You have previously agreed to allow your biological samples to be stored in a specific collection called "Infectious Diseases" (confirm with trial site)
You have had a brain or facial scan (CT or MRI) done as part of your regular medical care

Who may not be able to join:

You or your parents (if you are a child) do not want your medical data from your care to be used in this research study

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.

Last synced 27 July 2026

This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Voxsanity

Clinical trials and treatments, explained plainly · voxsanity.com.au

Date:

To: My Doctor

Re: Clinical trial enquiry

I am writing to enquire about the following clinical trial which may be relevant to my care:

Trial: NCT07422454

Sponsor: Imagine Institute

Phase: Not Applicable

Status: Recruiting

Condition: Rare Disease

More information: https://clinicaltrials.gov/study/NCT07422454

Eligibility summary (AI generated)

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

As a patient with one of these conditions:

You have been diagnosed with one of the following conditions: a skull growth condition linked to FGFR signaling (a gene pathway), achondroplasia or hypochondroplasia (types of dwarfism), osteogenesis imperfecta (brittle bone disease), or Pierre Robin sequence (a condition affecting jaw and airway development)
You have previously agreed to allow your biological samples (such as blood or tissue) to be stored in one of three specific medical collections related to bone and developmental conditions (confirm with trial site)
You have had a brain or facial scan (CT or MRI) done as part of your regular medical care

As a "control" participant (someone without these conditions):

You have visited the Genetics, Pediatrics, or Maxillofacial Surgery departments at Necker hospital and do NOT have any of the conditions listed above
You have previously agreed to allow your biological samples to be stored in a specific collection called "Infectious Diseases" (confirm with trial site)
You have had a brain or facial scan (CT or MRI) done as part of your regular medical care

Who may not be able to join:

You or your parents (if you are a child) do not want your medical data from your care to be used in this research study

⚠️ Important: Always verify eligibility with the trial site directly before applying.

Access in Australia: A treatment being studied in a clinical trial is generally not yet listed on the PBS. Where a medicine is not approved or not available through a trial, the TGA Special Access Scheme may allow a doctor to access unapproved therapeutic goods for individual patients. See voxsanity.com.au/sas-navigator/ for a plain English explainer.

This information was sourced from ClinicalTrials.gov via Voxsanity (data last synced 27 July 2026). It is not medical advice. Please verify the trial's current status directly with the trial site before acting.

Trial details

Status

Recruiting

Phase

Not Applicable

Sponsor

Imagine Institute

Registry

ClinicalTrials.gov

Start date

16 October 2025

Est. completion

31 October 2031

Where this trial is recruiting

🇫🇷 France

Primary endpoints

Characterization of the genotypic and phenotypic components of variability in rare genetic diseases with abnormalities of craniofacial development

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov