Obesity Trial, Recruiting NCT07428187 Sponsor: University of Colorado, Denver Condition: Obesity
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Obesity Trial, Recruiting

NCT07428187
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are between 25 and 45 years old
  • People with a Body Mass Index (BMI) of 27 or higher (BMI is a measure based on height and weight)
  • People who are comfortable taking part in a weight-loss program
  • People who are willing to eat a daily snack of either walnuts or pretzels as part of the study

Who may not be able to join:

  • People who have an allergy to nuts or wheat
  • People who have previously had weight-loss (bariatric) surgery
  • People who currently have an eating disorder
  • People who currently use illicit substances
  • People who are currently pregnant, breastfeeding, stopped breastfeeding less than 3 months ago, or are less than 6 months past giving birth
  • People with high blood pressure that is not well controlled (above 160/100 mmHg)
  • People with significant hormone, metabolic, kidney, liver, or blood conditions that could affect study results
  • People currently taking injectable medications, sulfonylureas, or meglitinides for diabetes treatment
  • People who have taken weight-loss medications or steroids (such as GLP-1 receptor agonists) within approximately 3 months before the study
  • People who have had significant mental health changes within approximately 3 months before the study, such as medication adjustments, new mental health diagnoses, or a hospital stay related to mental health
  • People with neurological (brain or nerve) illnesses or injuries that could affect MRI scan results
  • People whose weight has changed by more than 10% in the 3 months before the study
  • People who are currently taking part in another weight-loss study
  • People who are not comfortable eating the meals provided by the study or who follow a highly restrictive diet (such as a vegan diet)
  • People who cannot have an MRI scan, for example due to metal implants in the body or weighing more than 500 lbs (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Kristina T Legget, PhD, University of Colorado, Denver

Phone: 3037249024

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
5 March 2026
Est. completion
31 March 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Percent change in Blood Oxygen Level Dependent (BOLD) response to visual food cues as measured by functional magnetic resonance imaging

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov