Phase 1 Hypertension Trial, Recruiting NCT07428473 Sponsor: Monash University Condition: Hypertension
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Phase 1 Hypertension Trial, Recruiting

NCT07428473
Recruiting Phase 1 🇦🇺 Australian site

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have higher-than-normal levels of LDL cholesterol (sometimes called "bad" cholesterol) in their blood, whether or not they are currently taking medication to lower it
  • People who are willing and able to agree to participate before any study activities begin, and who are able to follow all study procedures throughout the trial

Who may not be able to join:

  • People who have had a heart attack, stroke, or similar cardiovascular event within the last 6 months
  • People who have any serious or uncontrolled health condition, or who have had a medical or surgical issue that could interfere with taking part in the study
  • People who have been diagnosed with familial hypercholesterolaemia, which is an inherited condition that causes very high cholesterol levels from birth
  • People who currently have, or have a history of, liver disease
  • People who have previously been treated with a type of cholesterol-lowering medication called a PCSK9 inhibitor, or certain other treatments within a specific time period before the trial (confirm with trial site for exact timeframes)
  • People whose blood test results show certain abnormal values that are considered clinically significant (confirm with trial site for specific details)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 8 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Stephen Nicholls, MBBS, FRACP, PhD, VHI

Phone: +61 423245187

Australian sites

Monash Health/ Victorian Heart Hospital (VHH), Clayton, Victoria
+61 3 7511 1252

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Monash University
Registry
ClinicalTrials.gov
Start date
1 June 2026
Est. completion
30 December 2028

Where this trial is recruiting

🇦🇺 Australia 🇳🇿 New Zealand

1 site(s) in Australia. Confirm current status and contact details directly with the trial site.

Primary endpoints

Incidence and Severity of Treatment-Emergent Adverse Events (TEAEs); Incidence and Severity of Serious Adverse Events (SAEs); Incidence and Severity of Adverse Events of Special Interest (AESI)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 8 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov