Phase 2 Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• People who have been diagnosed with a specific type of uterine cancer called endometrioid endometrial adenocarcinoma, confirmed by a biopsy or tissue sample taken within the past 8 weeks
• People aged 18 or older
• Women with this type of uterine cancer (any grade or stage) for whom surgery to remove the uterus is planned and considered appropriate
• People who have had a physical examination within roughly 6 weeks before the planned surgery
• People whose general health and ability to carry out daily activities falls within an acceptable range on a standard medical scale (ECOG score of 0, 1, 2, or 3), assessed within 28 days before joining
• People whose biopsy tissue has been preserved and stored in a way that makes it available for the study team to use
• People with blood counts, kidney function, and liver function results within the required ranges (confirm specific values with the trial site)
• People who have given written consent to participate and agreed to allow their health information to be shared for the study
• People of childbearing potential who have a negative pregnancy test before entering the trial

Who may not be able to join:

• People whose uterine cancer is a different type, such as serous, clear cell, carcinosarcoma, or a mixed type — only endometrioid adenocarcinoma is eligible
• People who received certain hormone-based treatments (progestins or anti-estrogen therapy) in the 3 months before their cancer diagnosis was confirmed (estrogen-only therapy is allowed)
• People whose general health falls into the most severely limited category on the standard medical scale (ECOG score of 4)
• People who have had a blood clot in a deep vein or in the lungs within the past 2 years, or who have an ongoing clotting disorder
• People who have previously received any treatment for uterine cancer, including surgery, radiation, or systemic therapy
• People whose stored biopsy tissue sample is too small or unavailable for the study
• People with a known or suspected peanut allergy
• People with serious other health conditions, a bowel blockage, or a condition affecting how the body absorbs food or medication, that would prevent them from taking tablets or capsules by mouth

Important: Always verify eligibility with the trial site directly before applying.