Phase 3 Lung Cancer Trial, Recruiting NCT07443397 Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences Condition: Lung Cancer
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Phase 3 Lung Cancer Trial, Recruiting

NCT07443397
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with small cell lung cancer (a specific type of lung cancer), confirmed by a laboratory test, where the cancer has spread to the brain — either at the time of first diagnosis or during treatment — and where the disease can be measured on scans.
  • People whose doctors estimate they are expected to live for more than 3 months.
  • People who have 10 or fewer areas of cancer spread in the brain.
  • People whose liver, kidneys, heart, and blood counts are working at an adequate level.
  • Women who could become pregnant must agree to use reliable birth control during the study and for 6 months after it ends.

Who may not be able to join:

  • People who have taken certain medications that target blood vessel growth (antiangiogenic drugs) within the past month.
  • People whose lung cancer is a different type, specifically non-small cell lung cancer or a mixed type that combines small cell and non-small cell cancer.
  • People whose small cell lung cancer has affected the airways near the centre of the chest or who have been coughing up blood.
  • People who have recently had a stroke or bleeding in the brain (confirm with trial site).
  • People who are still experiencing significant side effects (above a moderate level) from any previous cancer treatment.
  • People whose cancer has spread widely to internal organs and who are at short-term risk of serious, life-threatening complications.
  • People who have other serious or uncontrolled medical conditions that could be life-threatening.
  • People who have previously received radiation therapy to the brain.

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Lei Deng, MD, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Science and Peking Union Medical College

Phone: +86-010-87787625

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Registry
ClinicalTrials.gov
Start date
29 August 2025
Est. completion
31 August 2027

Where this trial is recruiting

🇨🇳 China

Primary endpoints

Intracranial progression-free survival

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov