Phase 3 Head and Neck Cancer Trial, Recruiting NCT07444723 Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Condition: Head and Neck Cancer
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Phase 3 Head and Neck Cancer Trial, Recruiting

NCT07444723
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People aged 18 to 100 years old
  • People who are willing to have parathyroid surgery at the NIH Clinical Center
  • People who have been diagnosed with sporadic primary hyperparathyroidism (a condition where one or more parathyroid glands produce too much parathyroid hormone) and are being considered for parathyroid surgery
  • People who have been diagnosed with an inherited form of primary hyperparathyroidism — including first-time or returning cases — and are being considered for parathyroid surgery; this includes people suspected of having multiple affected glands or a genetic condition linked to parathyroid disease
  • People who are suspected of having, or have been diagnosed with, parathyroid cancer and are being considered for parathyroid surgery

Who may not be able to join:

  • People who are pregnant or breastfeeding
  • People who have had a known allergic reaction to the components of the imaging agent called 18F-Fluorocholine
  • People who are capable of becoming pregnant and are not willing to use highly effective contraception for at least two weeks before the first imaging scan through to the date of surgery
  • People who have used an investigational (experimental) drug or medical device in the 30 days before the imaging scan, not including a specific type of scan called an F-DOPA scan
  • People who are unable or unwilling to give informed consent to participate
  • People who have any other health condition that, in the opinion of the research doctors, would make it unsafe for them to complete the study (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 23 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Smita Jha, M.D., National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Phone: (301) 435-7921

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Registry
ClinicalTrials.gov
Start date
16 April 2026
Est. completion
5 February 2035

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Evaluate positive predictive value of 18F-FCH PET/MRI and PET/CT in participants with sporadic primary hyperparathyroidism (PHPT); Evaluate positive predictive value of 18F-FCH PET/MRI and PET/CT in participants with sporadic primary hyperparathyroidism (PHPT)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 23 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov