Phase 1 Endometrial Cancer Trial, Recruiting NCT07444814 Sponsor: Whitehawk Therapeutics, Inc. Condition: Endometrial Cancer
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Phase 1 Endometrial Cancer Trial, Recruiting

NCT07444814
Recruiting Phase 1

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have a specific type of lung cancer called non-squamous EGFR-Wt non-small cell lung cancer (a form of lung cancer where a particular gene marker, EGFR, is not mutated — confirm with trial site)
  • People who have endometrial carcinoma (a cancer of the lining of the uterus)
  • People who have ovarian cancer that has stopped responding to platinum-based treatment

Who may not be able to join:

  • People who have cancer that has spread to the brain or spinal cord in a way that is not well controlled
  • People who have a history of cancer spreading to the membranes surrounding the brain or spinal cord
  • People who have an active infection — bacterial, viral, fungal, or parasitic — that is not under control
  • People who have a known condition affecting the clear surface of the eye (cornea), or who have had a cornea transplant
  • People who still have significant unresolved side effects from a previous cancer treatment
  • People who have serious heart disease
  • People whose heart's electrical activity shows a specific abnormality on an ECG reading (a QTcF measurement of 470 milliseconds or more — confirm with trial site)
  • People who have a history of lung inflammation or scarring (pneumonitis or interstitial lung disease)
  • People who are pregnant, breastfeeding, or planning to breastfeed during the study or within 30 days of the last dose of the study treatment

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 19 July 2026
Phase 1: approximately ~10% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Margaret C Dugan, MD, Whitehawk Therapeutics

Phone: 888-392-9025

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 1
Sponsor
Whitehawk Therapeutics, Inc.
Registry
ClinicalTrials.gov
Start date
19 December 2025
Est. completion
1 October 2028

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Determine Maximum Tolerated Dose (MTD); Determine Maximum Administered Dose (MAD); Determine the Recommended Dose for Expansion (RDE)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 19 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov