Phase 3 Obesity Trial, Recruiting NCT07446439 Sponsor: Vanda Pharmaceuticals Condition: Obesity
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Phase 3 Obesity Trial, Recruiting

NCT07446439
Recruiting Phase 3

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with a Body Mass Index (BMI) of 25 or above but below 40 (a measure of body weight relative to height)
  • People who do not have serious medical problems or chronic diseases, and specifically do not have type 1 or type 2 diabetes

Who may not be able to join:

  • People who have another condition that causes stomach or digestive symptoms
  • People who have had a bad reaction or sensitivity to a type of medication known as NK-1 receptor antagonists
  • People who have had a bad reaction or sensitivity to a type of medication known as GLP-1 receptor agonists (a class of medicines sometimes used for blood sugar or weight management)
  • People who have taken part in another medical study and received an experimental medication within the past 60 days

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 14 July 2026
Phase 3: approximately ~65% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Vanda Pharmaceuticals Inc., Vanda Pharmaceuticals Inc.

Phone: (202) 734-3400

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 3
Sponsor
Vanda Pharmaceuticals
Registry
ClinicalTrials.gov
Start date
27 March 2026
Est. completion
1 December 2026

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Proportion of participants with at least 1 vomiting episode per week in the tradipitant group compared to the placebo group as measured by a daily symptom diary.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 14 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov