Phase 2 Melanoma Trial, Recruiting NCT07449754 Sponsor: Hanmi Pharmaceutical Company Limited Condition: Melanoma
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Phase 2 Melanoma Trial, Recruiting

NCT07449754
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who have been diagnosed with melanoma that has spread locally or to other parts of the body, confirmed by laboratory testing of tissue or cell samples, and for whom standard treatments have not worked, are no longer working, or cannot be tolerated
  • People whose melanoma has a specific genetic change called an NRAS mutation
  • People who have at least one area of cancer that can be measured on scans, according to standard measurement guidelines (called RECIST v1.1)
  • People who are generally able to carry out daily activities, rated as 0, 1, or 2 on a standard health and activity scale (called the ECOG performance status scale)
  • People aged 19 years or older
  • People whose kidneys, blood, and liver are functioning adequately based on test results

Who may not be able to join:

  • People who have previously been treated with certain types of targeted cancer drugs known as RAF inhibitors, MEK inhibitors, or ERK inhibitors
  • People who have a past or current eye condition affecting the retina that may increase the risk of certain eye problems (confirm with trial site)
  • People who have a past or current condition affecting how the heart functions
  • People who experienced a serious bleeding episode (rated Grade 3 or higher on a standard side effect scale) within the 4 weeks before the first planned dose of the study drug

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 27 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Phone: 82-2-410-9277

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Hanmi Pharmaceutical Company Limited
Registry
ClinicalTrials.gov
Start date
12 February 2026
Est. completion
1 September 2029

Where this trial is recruiting

🇰🇷 South Korea

Primary endpoints

Objective response rate (ORR)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 27 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov