Phase 1 Endometrial Cancer Trial, Recruiting

Written by an AI model from ClinicalTrials.gov eligibility criteria and checked on a sample basis. Please confirm against the original criteria.

Who might be able to join this trial:

• You must be 18 years of age or older.
• You must be willing and able to sign a consent form agreeing to take part in the trial.
• You must have been diagnosed with a specific type of advanced cancer (such as non-small cell lung cancer, pancreatic cancer, colorectal cancer, or another solid tumor) that has spread or cannot be surgically removed, confirmed through a tissue sample.
• Your cancer must have been tested and confirmed to have a specific gene change called a KRAS mutation before starting the trial.
• Your cancer must have gotten worse during standard treatment, or you were unable to tolerate standard treatment.
• You must be generally well enough to carry out daily activities with little or no limitation, as measured by a standard health score (confirm with trial site).
• Your heart, blood, liver, and kidneys must be functioning well enough to meet the trial's requirements.
• Your cancer must be measurable on scans at the start of the trial, according to standard measurement guidelines.

Who may not be able to join:

• You have previously received or are currently receiving a treatment that targets the RAS or KRAS gene.
• Your cancer has spread to the brain or spinal cord, or you have a tumor in the brain.
• You are unable to swallow tablets or capsules taken by mouth.
• You are pregnant, breastfeeding, or planning to become pregnant or father a child during the trial period.

Important: Always verify eligibility with the trial site directly before applying.