Phase 2 Obesity Trial, Recruiting NCT07463846 Sponsor: Alnylam Pharmaceuticals Condition: Obesity
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Phase 2 Obesity Trial, Recruiting

NCT07463846
Recruiting Phase 2

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People with a body mass index (BMI) of 30 or above but below 40 (this is a common measure of body weight relative to height)
  • People with an HbA1c level below 6.5% (this is a blood test result that shows average blood sugar levels over the past few months)

Who may not be able to join:

  • People with a significant ongoing health condition, illness, or unusual test results that could affect their safety or make the trial results harder to interpret
  • People who are currently taking medications for long-term weight management or for controlling blood sugar levels

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 20 July 2026
Phase 2: approximately ~30% of drugs entering this phase reach regulatory approval, based on published industry-wide historical data. This is not specific to this trial.
Phase success rates shown are historical industry-wide averages based on published data. They are not a prediction for this specific trial or your individual situation.

Contact this trial

Principal Investigator: Medical Director, Alnylam Pharmaceuticals

Phone: 1-877-ALNYLAM

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Phase 2
Sponsor
Alnylam Pharmaceuticals
Registry
ClinicalTrials.gov
Start date
2 March 2026
Est. completion
27 April 2027

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Part A: Frequency of Adverse Events (AEs); Part B: Percent Change from Baseline in Body Weight; Part C: Percent Change from Baseline in Body Weight

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 20 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov