Head and Neck Cancer Trial, Recruiting NCT07475780 Sponsor: M.D. Anderson Cancer Center Condition: Head and Neck Cancer
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Head and Neck Cancer Trial, Recruiting

NCT07475780
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • People who are older than 18 years and are either not suitable for surgery or do not wish to have surgery
  • People who are healthy enough to undergo a procedure using local anaesthetic, with or without light sedation
  • People who are able to understand the study information and agree to take part
  • People who have a confirmed diagnosis of parathyroid cancer, established through a previous surgery and laboratory tissue analysis
  • People who have a return of cancer in the neck, or a cancer deposit in the neck, that can be seen on an ultrasound scan
  • People who have a small number of cancer spots that have spread to distant sites but are visible on ultrasound
  • People whose target growth is solid, without large calcium deposits or fluid-filled areas inside it
  • People who are not currently taking the medication Cinacalcet
  • People whose target growth can be fully seen on ultrasound and does not extend significantly behind the windpipe or into the chest area (confirm with trial site for specific classification types)
  • People whose target growth can be approached from the middle or side during the procedure
  • People with normal blood count and normal blood clotting results
  • People who agree to attend all required study visits and assessments
  • Women who could potentially be pregnant must have a negative pregnancy test before the procedure

Who may not be able to join:

  • People who have an irregular heartbeat or who have an implanted heart device (such as a pacemaker)
  • People whose parathyroid growth has never been operated on before, or whose growth is a non-cancerous parathyroid adenoma or borderline parathyroid tumour
  • People who are pregnant
  • People who have known allergies to anaesthetic medications
  • People whose target growth is mostly fluid-filled (less than 70% solid tissue)
  • People whose target growth contains calcium deposits
  • People whose target growth is within half a centimetre of major blood vessels or important nerves in the neck (including the vagus nerve, brachial plexus, or recurrent laryngeal nerve)
  • People who have paralysis of the vocal cord on the opposite side of the neck to the target growth
  • People with blood clotting problems that cannot be corrected, based on specific laboratory values (confirm with trial site)

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 6 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

Contact this trial

Principal Investigator: Thinh Vu, MD, UT MD Anderson

Phone: (281) 415-2061

Contact details sourced from ClinicalTrials.gov. Verify directly with the trial site before attending.

GP referral letter

Print a one-page summary to share with your doctor.

Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
9 April 2026
Est. completion
30 April 2029

Where this trial is recruiting

🇺🇸 United States

Primary endpoints

Safety and Adverse Events (AEs)

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 6 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov