Brain Cancer Trial, Recruiting NCT07476781 Sponsor: Sunnybrook Health Sciences Centre Condition: Brain Cancer
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Brain Cancer Trial, Recruiting

NCT07476781
Recruiting Not Applicable

Who may be able to join

AI generated eligibility summary. Written by an AI model from the official source data and checked on a sample basis. It can contain mistakes, so confirm anything important against the original source. How we use AI

Who might be able to join this trial:

  • You have been diagnosed with a solid tumour cancer that has spread to other parts of the body, and you fall into one of three groups: (A) cancer that has spread to the fluid around the brain and/or spinal cord (with or without tumours in the brain itself), (B) tumours in the brain but no spread to the fluid around the brain/spinal cord, or (C) cancer that has spread elsewhere in the body but not to the brain or its surrounding fluid.
  • You are able to have a lumbar puncture (a procedure to collect fluid from around the spine) and/or you already have a special device called an Ommaya reservoir that can be used to collect fluid from around the brain.
  • You can join at any stage of your treatment — whether you have already started treatment or not.
  • You have brain tumours that are either newly found and not yet treated, or were previously treated but are now growing again.
  • If you were in this study before but your results were negative, you may be able to re-join if your condition has since changed or worsened.

Who may not be able to join:

  • You are unable or unwilling to give written consent to participate (note: not speaking English is not a barrier — a translator can be used).
  • You are not able to safely have a lumbar puncture — for example, due to infection near the procedure site, uncontrolled bleeding problems, a very low platelet count, blood-thinning medications that cannot be safely stopped, a risk of a dangerous pressure shift in the brain, or having metal hardware in your spine (confirm with trial site for full details).

Important: Always verify eligibility with the trial site directly before applying.

Based on publicly available eligibility criteria from ClinicalTrials.gov. Verify directly with the trial site before acting. This is not medical advice.

This is a simplified plain English summary of the eligibility criteria. Full criteria are set by the trial investigators and may include additional requirements not shown here. Never self-exclude from a trial based on this summary. Contact the trial site directly to confirm your eligibility.
Last synced 2 July 2026
This study is not part of the standard drug-approval phase pathway (for example an observational, device, behavioural, or registry study), so a phase success rate does not apply.

GP referral letter

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Trial details

Status
Recruiting
Phase
Not Applicable
Registry
ClinicalTrials.gov
Start date
12 December 2025
Est. completion
1 December 2026

Where this trial is recruiting

🇨🇦 Canada

Primary endpoints

Number of patients with positive cerebrospinal fluid (CSF) biomarkers in each cohort.

Can't join this trial?

Expanded access pathways

If this trial is not available to you, other access pathways may exist. In Australia, the TGA Special Access Scheme allows access to unapproved therapeutic goods for individual patients.

TGA Special Access Scheme information

Find other recruiting trials on ClinicalTrials.gov

Data last synced from ClinicalTrials.gov: 2 July 2026. Trial status can change. Always verify current status directly with the trial site before making any decision.

Trial recruitment status can change without notice between our nightly data updates. Always contact the trial site directly to confirm current recruitment status before making any decisions or travel arrangements.

View original record on ClinicalTrials.gov